- For Lease Contact for pricing
- Property Type Office - General Office
- Property Size 387,943 SF
- Lot Size 1.08 Acre
- Parking Spaces Avail. 108
- Parking Ratio 0.28 / 1,000 SF
- Property Tenancy Multi-Tenant
- LEED Certified Platinum
- Building Class A
- Year Built 1973
- Date Updated Mar 12, 2025
221 Main is a 387,943-square-foot general office building in South Beach, offering LEED Platinum certification for eco-conscious tenants. Set on a 1.08-acre lot, the property includes 108 parking spaces with a parking ratio of 0.28, making it a sustainable and functional choice for businesses seeking a professional workspace.
South Beach provides exceptional accessibility and amenities, with numerous public transportation options, including Market Street stations within approximately 0.5 miles, and taxi stands as close as 0.2 miles. Dining options are abundant, with restaurants like Sweetgreen, Proper Food, and Epic Steak all within a short walk. Nearby hotels, such as Harbor Court Hotel and Hotel Griffon, offer convenient accommodations for visiting clients or employees. For additional parking, the 201 Spear Upper Lot is just steps away.
Reach out to the broker for more info on lease terms and amenities
True
Spaces Available
#1000 |
Amazing Bay Bridge & Water Views
Fully Furnished
2 Large Conference Rooms
4 Medium Conference Rooms
14 Private Offices/ Huddle Rooms
8 Focus Rooms
Open Area - Room for 160+ Workstations
Large Kitchen/ Break Area
Wellness Room
Storage Room
IDF Room |
#1100 |
Full reception area
160 desks
28 offices
Boardroom with sweeping Bay views
Training room
Game room
Refreshed restrooms and gallery kitchen |
#1200 |
Amazing Bay Bridge & Water Views
Fully Furnished
Open Ceiling
3 Large Conference Rooms
4 Medium Conference Rooms
12 Private Offices/ Huddle Rooms
2 Focus Rooms
Open Area - Room For 120+ Workstations
Large Kitchen/ Break Area
Storage Room
IDF Room |
#1650 |
17 private offices
2 large conference rooms
2 medium conference rooms
Kitchenette/break area
Open Area | 25 6’ x 8’ Workstations
Copy Area
Storage Room
Wellness Room
Partically Exposed Ceilings |
#400 |
3 private offices/meeting rooms
1 conference room
Kitchen
Open area |
#500 |
Amazing bay views |
#600 & 650 |
20 private offices
3 medium/large conference rooms
3 kitchenettes
Amazing views
Divisible to 8,319 RSF
Open area
Great natural light |
#770 |
2 private offices/meeting rooms
1 conference room
Large open space
Kitchenette
Great natural light |
11th Floor |
PLUG & PLAY SUBLEASE WITH BAY VIEWS ? Full reception area ? 160 desks ? 28 offices ? Board room with sweeping Bay views ? Training room ? Game room ? Refreshed restrooms and galley kitchen |
6th Floor |
PLUG & PLAY SUBLEASE WITH BAY VIEWS ? Full reception area ? 118 desks ? 21 offices ? Training/board room ? 2 kitchens and one kitchenette |
Contacts
Location
Getting Around
-
Walk Score ®
97/100 Walker's Paradise
-
Transit Score ®
100/100 Rider's Paradise
-
Bike Score ®
80/100 Very Bikeable
- City San Francisco, CA
- Neighborhood South Beach
- Zip Code 94105
- Market San Francisco
Points of Interest
-
Taxi Stand at Hotel Vitale
0.23 miles
-
Taxi Stand at Farmers Market near Ferry Building
0.23 miles
-
Taxi Stand at Salesforce Transit Center
0.27 miles
-
Market Street & Drumm Street
0.31 miles
-
Market Street & Main Street
0.31 miles
-
California Street & Drumm Street
0.33 miles
-
Taxi Stand at 101 California St Building (along Davis St)
0.35 miles
-
Taxi Stand at Hyatt Regency (along Drumm St)
0.36 miles
-
California Street & Davis Street
0.38 miles
-
Market Street & Battery Street
0.38 miles
-
Shell
0.69 miles
-
Chevron
1.14 miles
-
EVgo
1.50 miles
-
Volta HQ Charging Station
1.62 miles
-
76
1.64 miles
-
Standard
1.67 miles
-
Tesla Destination Charger
2.04 miles
-
Arco
2.16 miles
-
Electrify America
2.19 miles
-
Rivian Waypoints
2.27 miles
-
201 Spear Upper Lot
0.07 miles
-
ace parking
0.50 miles
-
Palace Garage
0.51 miles
-
Embarcadero Center 1 Parking
0.53 miles
-
SFMOMA Garage
0.53 miles
-
Golden Gateway Garage
0.54 miles
-
Moscone Center Garage
0.56 miles
-
550 California Street Parking Garage
0.66 miles
-
Jessie Square Garage
0.68 miles
-
The White House Garage
0.68 miles
-
Harbor Court Hotel
0.16 miles
-
Hotel Griffon
0.17 miles
-
Hotel Vitale
0.23 miles
-
Hyatt Regency San Francisco
0.35 miles
-
The Clancy, Autograph Collection
0.40 miles
-
The Jay, Autograph Collection
0.56 miles
-
Palace Hotel
0.57 miles
-
W San Francisco
0.58 miles
-
Club Quarters Hotel, San Francisco, Embarcadero
0.58 miles
-
The St. Regis San Francisco
0.59 miles
-
Sweetgreen
0.06 miles
-
Prospect
0.07 miles
-
Proper Food
0.08 miles
-
Mau
0.09 miles
-
SOMA Eats
0.10 miles
-
Nick The Greek
0.11 miles
-
Tokyo Express
0.12 miles
-
Epic Steak
0.15 miles
-
Ozumo
0.16 miles
-
Waterbar
0.16 miles
-
Bodhi Panya Institute
0.29 miles
-
Golden Gate University
0.39 miles
-
University of Phoenix
0.40 miles
-
Academy of Art University
0.49 miles
-
Academy of Art University - Game Development
0.50 miles
-
Saybrook University
0.69 miles
-
Edwin and Anita Lee Newcomer School
0.72 miles
-
City College of San Francisco Chinatown Annex
0.75 miles
-
Cogswell College
0.77 miles
-
City College of San Francisco (CCSF) North Beach / Chinatown
0.78 miles
-
Bright Horizons
0.42 miles
-
SOMA Daycare & Preschool
0.62 miles
-
Yerba Buena Gardens Child Development Center
0.74 miles
-
Chinatown Community Children's Center
0.96 miles
-
Telegraph Hill Cooperative Nursery School
1.07 miles
-
Happy Trails
1.20 miles
-
Compass Children's Center
1.31 miles
-
L’Academy
1.47 miles
-
Mission Montessori
1.74 miles
-
Golden Gate Kindergarten
2.03 miles
Frequently Asked Questions
The property includes 10 Office spaces located on 8 floors. Availabilities total 178,751 square feet of office space. The property offers Multi-Tenant commercial space. Of the availability currently listed in the building, available spaces include 2 sublease options.
Yes, availabilities here may be suitable for small businesses with 1 office space under 5,000 square feet available.
Yes, availabilities here could accommodate larger businesses with 8 office spaces larger than 10,000 square feet available for lease. The largest office size is 32,026 SF, located on floor 6. For a better understanding of how this space could work for you, reach out to schedule a tour.
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