221 Main

221 Main Street, San Francisco, CA 94105

  • For Lease Contact for pricing
  • Property Type Office - General Office
  • Property Size 387,943 SF
  • Lot Size 1.08 Acre
  • Parking Spaces Avail. 108
  • Parking Ratio 0.28 / 1,000 SF
  • Property Tenancy Multi-Tenant
  • LEED Certified Platinum
  • Building Class A
  • Year Built 1973
  • Date Updated Mar 12, 2025

221 Main is a 387,943-square-foot Class A office building with Platinum LEED certification, situated on a 1.08-acre lot in the heart of South Beach. Built with modern sustainability in mind, the property provides 108 parking spaces with a parking ratio of 0.28. Its design and features cater to businesses seeking a professional environment that aligns with eco-conscious values.

The surrounding South Beach neighborhood offers a vibrant mix of amenities and conveniences. Transportation options are abundant, with Market Street & Drumm Street and Market Street & Main Street approximately 0.3 miles away, both within walking distance. Dining options such as Sweetgreen, Prospect, and Mau are less than 0.1 miles away, while hotels like Harbor Court Hotel and Hotel Griffon are less than 0.2 miles from the property. Nearby education institutions, including Golden Gate University and the Academy of Art University, are within 0.5 miles. This dynamic location balances accessibility with a lively urban environment.

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Reach out to the broker for more info on lease terms and amenities

Spaces Available

Contacts

broker
Wesley Powell Is this you?

Jones Lang LaSalle

broker
Steve Anderson Is this you?

Jones Lang LaSalle

broker
Jason Volpe Is this you?

Jones Lang LaSalle

broker
John Roskos Is this you?

Jones Lang LaSalle

broker
Lexi Castellino Is this you?

Jones Lang LaSalle

Location

Getting Around

  • Walk Score ®

    97/100 Walker's Paradise

  • Transit Score ®

    100/100 Rider's Paradise

  • Bike Score ®

    80/100 Very Bikeable
Powered by Walk Score ®
  • City San Francisco, CA
  • Neighborhood South Beach
  • Zip Code 94105
  • Market San Francisco

Points of Interest

  • Taxi Stand at Hotel Vitale

    0.23 miles

  • Taxi Stand at Farmers Market near Ferry Building

    0.23 miles

  • Taxi Stand at Salesforce Transit Center

    0.27 miles

  • Market Street & Drumm Street

    0.31 miles

  • Market Street & Main Street

    0.31 miles

  • California Street & Drumm Street

    0.33 miles

  • Taxi Stand at 101 California St Building (along Davis St)

    0.35 miles

  • Taxi Stand at Hyatt Regency (along Drumm St)

    0.36 miles

  • California Street & Davis Street

    0.38 miles

  • Market Street & Battery Street

    0.38 miles

  • Shell

    0.69 miles

  • Chevron

    1.14 miles

  • EVgo

    1.50 miles

  • Volta HQ Charging Station

    1.62 miles

  • 76

    1.64 miles

  • Standard

    1.67 miles

  • Tesla Destination Charger

    2.04 miles

  • Arco

    2.16 miles

  • Electrify America

    2.19 miles

  • Rivian Waypoints

    2.27 miles

  • 201 Spear Upper Lot

    0.07 miles

  • ace parking

    0.50 miles

  • Palace Garage

    0.51 miles

  • Embarcadero Center 1 Parking

    0.53 miles

  • SFMOMA Garage

    0.53 miles

  • Golden Gateway Garage

    0.54 miles

  • Moscone Center Garage

    0.56 miles

  • 550 California Street Parking Garage

    0.66 miles

  • Jessie Square Garage

    0.68 miles

  • The White House Garage

    0.68 miles

  • Harbor Court Hotel

    0.16 miles

  • Hotel Griffon

    0.17 miles

  • Hotel Vitale

    0.23 miles

  • Hyatt Regency San Francisco

    0.35 miles

  • The Clancy, Autograph Collection

    0.40 miles

  • The Jay, Autograph Collection

    0.56 miles

  • Palace Hotel

    0.57 miles

  • W San Francisco

    0.58 miles

  • Club Quarters Hotel, San Francisco, Embarcadero

    0.58 miles

  • The St. Regis San Francisco

    0.59 miles

  • Sweetgreen

    0.06 miles

  • Prospect

    0.07 miles

  • Proper Food

    0.08 miles

  • Mau

    0.09 miles

  • SOMA Eats

    0.10 miles

  • Nick The Greek

    0.11 miles

  • Tokyo Express

    0.12 miles

  • Epic Steak

    0.15 miles

  • Ozumo

    0.16 miles

  • Waterbar

    0.16 miles

  • Bodhi Panya Institute

    0.29 miles

  • Golden Gate University

    0.39 miles

  • University of Phoenix

    0.40 miles

  • Academy of Art University

    0.49 miles

  • Academy of Art University - Game Development

    0.50 miles

  • Saybrook University

    0.69 miles

  • Edwin and Anita Lee Newcomer School

    0.72 miles

  • City College of San Francisco Chinatown Annex

    0.75 miles

  • Cogswell College

    0.77 miles

  • City College of San Francisco (CCSF) North Beach / Chinatown

    0.78 miles

  • Bright Horizons

    0.42 miles

  • SOMA Daycare & Preschool

    0.62 miles

  • Yerba Buena Gardens Child Development Center

    0.74 miles

  • Chinatown Community Children's Center

    0.96 miles

  • Telegraph Hill Cooperative Nursery School

    1.07 miles

  • Happy Trails

    1.20 miles

  • Compass Children's Center

    1.31 miles

  • L’Academy

    1.47 miles

  • Mission Montessori

    1.74 miles

  • Golden Gate Kindergarten

    2.03 miles

Frequently Asked Questions

What type of office space is available to lease at 221 Main?

The property includes 10 Office spaces located on 8 floors. Availabilities total 178,751 square feet of office space. The property offers Multi-Tenant commercial space. Of the availability currently listed in the building, available spaces include 2 sublease options.

Is 221 Main suitable for a small business?

Yes, availabilities here may be suitable for small businesses with 1 office space under 5,000 square feet available.

Does 221 Main have enough space for a large business?

Yes, availabilities here could accommodate larger businesses with 8 office spaces larger than 10,000 square feet available for lease. The largest office size is 32,026 SF, located on floor 6. For a better understanding of how this space could work for you, reach out to schedule a tour.

Does 221 Main have parking?
Yes, the property offers 108 parking spaces with a parking ratio of 0.28 / 1,000 SF.
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