Clayton, St. Louis County, MO Commercial Real Estate for Lease and Sale

Explore 48 listings of Clayton commercial real estate to find the best space for your business.

7710-7730 Carondelet Avenue

7730 Carondelet Avenue, Clayton, St. Louis, MO
Property

Office

89,470 SF
Availability

4 Spaces

23,484 SF
Year Built

1989
For Lease

$21.00/SF/YR
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8235 Forsyth Blvd

8235 Forsyth Blvd, Clayton, St. Louis, MO
Property

Office

244,800 SF
Availability

8 Spaces

55,610 SF
Year Built

2000
For Lease

$31.00/SF/YR
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200 South Hanley Road

200 South Hanley Road, Clayton, MO
Property

Office

122,850 SF
Availability

1 Space

30,210 SF
Year Built

1967
For Lease

$18.00/SF/YR
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Bemiston Tower

231 South Bemiston Avenue, Clayton, St. Louis, MO
Property

Office

174,241 SF
Availability

2 Spaces

17,516 SF
Year Built

1982
For Lease Contact for pricing
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What type of listing property are you looking for?

Office Coworking Retail

Office Retail Land
Shaw Park Plaza

1 N. Brentwood Blvd., Clayton, MO
Property

Office

281,562 SF
Availability

4 Spaces

18,102 SF
Year Built

2001
For Lease

$40.50/SF/YR
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Centene Plaza Building B

7700 Forsyth Blvd., Clayton, MO
Property

Office

465,654 SF
Availability

2 Spaces

55,332 SF
Year Built

2010
For Lease

$45.00/SF/YR
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The Hunter Building

121 Hunter Avenue, Clayton, St. Louis, MO
Property

Office

33,318 SF
Availability

1 Space

5,840 SF
Year Built

1987
For Lease

$21.50/SF/YR
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The Hoffmann Building

8000 Maryland Ave., Clayton, MO
Property

Office

194,045 SF
Availability

15 Spaces

59,002 SF
Year Built

1983
For Lease

$30.00/SF/YR
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Hanley Corporate Tower

101 South Hanley Road, Clayton, St. Louis, MO
Property

Office

346,451 SF
Availability

7 Spaces

44,671 SF
Year Built

1985
For Lease

$33.50/SF/YR
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Centene Plaza Building C

7676 Forsyth Blvd., Clayton, MO
Property

Office

617,515 SF
Availability

2 Spaces

39,080 SF
Year Built

2019
For Lease

$45.00/SF/YR
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The Plaza in Clayton

190 Carondelet Plaza, Clayton, St. Louis, MO
Property

Office

325,172 SF
Availability

2 Spaces

11,330 SF
Year Built

2002
For Lease

$38.75/SF/YR
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8151 Clayton Road

8151 Clayton Road, Clayton, MO
Property

Office

32,000 SF
Availability

1 Space

2,709 SF
Year Built

1989
For Lease

$25.00/SF/YR
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7801 Clayton Rd

7801 Clayton Rd, Clayton, Saint Louis, MO
Property

Office

6,240 SF
Availability

1 Space

1,658 SF
Year Built

1940
For Lease

$1,900.00/MO
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Sevens Building

7777 Bonhomme Ave., Clayton, MO
Property

Office

197,311 SF
Availability

21 Spaces

49,848 SF
Year Built

1972
For Lease

$30.00/SF/YR
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Pierre Laclede II

7733 Forsyth Blvd, Clayton, MO
Property

Office

361,235 SF
Availability

12 Spaces

105,418 SF
Year Built

1970
For Lease

$32.00/SF/YR
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Clayton Office Evolution
Office Evolution
231 South Bemiston Avenue Suite 800, St. Louis, MO
Services

Virtual Office

Open Workspace

Meeting Room
Amenities

Bike storage

Complimentary coffee & tea

Free water

High-speed wifi

Parking
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230 South Bemiston Avenue

230 South Bemiston Avenue, Clayton, MO
Property

Office

109,130 SF
Availability

7 Spaces

14,866 SF
Year Built

1963
For Lease

$23.50 - $25.00/SF/YR
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The 130 Building

130 South Bemiston Avenue, Clayton, St. Louis, MO
Property

Office

73,969 SF
Availability

9 Spaces

19,827 SF
Year Built

1964
For Lease Contact for pricing
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The 222 Building

222 South Central Avenue, Clayton, St. Louis, MO
Property

Office

127,000 SF
Availability

8 Spaces

33,902 SF
Year Built

1968
For Lease

$26.50/SF/YR
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Pierre Laclede I

7701 Forsyth Blvd., Clayton, MO
Property

Office

217,668 SF
Availability

12 Spaces

74,729 SF
Year Built

1964
For Lease

$32.00/SF/YR
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Old Town - 168 North Meramec Avenue

168 North Meramec Avenue, Clayton, St. Louis, MO
Property

Office

59,252 SF
Availability

3 Spaces

24,713 SF
Year Built

1982
For Lease

$23.50 - $28.00/SF/YR
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10 North Hanley Road

10 North Hanley Road, Clayton, MO
Property

Office

33,000 SF
Availability

2 Spaces

26,400 SF
Year Built

1963
For Lease

$23.00/SF/YR
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Parkway Tower

225-235 S Meramec Ave, Clayton, MO
Property

Office

102,600 SF
Availability

10 Spaces

12,043 SF
For Lease

$21.50/SF/YR
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Clayton - St. Louis
Serendipity Labs
8112 Maryland Avenue, Clayton, MO
Services

Virtual Office

Open Workspace

Meeting Room

Private Office

Dedicated Desk
Amenities

Complimentary coffee & tea

Free water

High-speed wifi

IT support

Parking

Premium coffee

Printer

Privacy booths

Projector

Receptionist/Secretarial services
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The Bank of America Building

7800 Forsyth Blvd, Clayton, MO
Property

Office

100,487 SF
Availability

1 Space

4,469 SF
Year Built

1985
For Lease

$29.50/SF/YR
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Sevens Building
Regus
7777 Bonhomme Ave Suite 1800, Clayton, MO
Services

Virtual Office

Open Workspace

Private Office

Dedicated Desk
Amenities

24/7 security

Access to global network

Business address

Business lounge

Cleaning services

Ergonomic furniture

Lounge area

Mail services

Money-back guarantee

Office furniture
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Hoffmann Building

8000 Maryland Avenue, Clayton, St. Louis, MO
Property

Office

194,045 SF
Availability

1 Space

2,178 SF
Year Built

1983
For Lease Contact for pricing
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230 South Bemiston Avenue

230 South Bemiston Avenue, Clayton, MO
Property

Office

109,130 SF
Availability

2 Spaces

5,084 SF
Year Built

1964
For Lease

$22.50 - $23.50/SF/YR
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PNC Center

120 S Central Ave , Clayton, MO
Property

Office

301,613 SF
Availability

10 Spaces

75,360 SF
For Lease

$31.00/SF/YR
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Francis Place

950 Francis Place, Clayton, MO
Property

Office

61,200 SF
Year Built

1955
For Sale

$7,500,000
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Forsyth Pointe - West Tower

8049 Forsyth Blvd, Clayton, MO
Property

Office

220,085 SF
Availability

2 Spaces

5,732 SF
Year Built

2023
For Lease Contact for pricing
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Clayton Executive Center I

7930 Clayton Rd , Clayton, St Louis, MO
Property

Office

139,308 SF
Availability

2 Spaces

35,305 SF
Year Built

1982
For Lease

$26.00/SF/YR
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Francis Place

950 Francis Place, Clayton, MO
Property

Office

61,200 SF
Availability

5 Spaces

8,861 SF
For Lease

$12.00 - $22.00/SF/YR
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Regions Centre

8182 Maryland Avenue, Clayton, St. Louis, MO
Property

Office

278,800 SF
Availability

9 Spaces

100,152 SF
Year Built

1985
For Lease

$31.00/SF/YR
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Pierre Laclede
Regus
7733 Forsyth Boulevard Suite 1100, Clayton, MO
Services

Virtual Office

Open Workspace

Private Office

Dedicated Desk
Amenities

24/7 security

Access to global network

Business address

Business lounge

Cleaning services

Ergonomic furniture

Lounge area

Mail services

Money-back guarantee

Office furniture
View Details (opens in new window)
168 North Meramec Avenue
Alchemy
168 North Meramec Avenue #150, Clayton, MO
Services

Open Workspace

Event Space

Meeting Room

Private Office
Amenities

Gym

High-speed internet

Kitchen

Parking

Professional & social events

Shower

TV/Monitor

Women-focused
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507 S Hanley Road

507 S Hanley Road, Clayton, St. Louis, MO
Property

Retail

1,870 SF
Availability

1 Space

1,870 SF
For Lease

$25.00/SF/YR
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Ceylon Shops

33 N Central Ave, Clayton, MO
Property

Retail

13,585 SF
Availability

1 Space

2,126 SF
For Lease

$34.00/SF/YR
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1-9 N. Central Ave.

1 N. Central Avenue , Clayton, MO
Property

Retail

8,609 SF
Availability Contact for availability
Year Built

1900
For Lease Contact for pricing
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6369 Clayton Rd

6369 Clayton Rd, Clayton, MO
Property

Retail

7,200 SF
For Sale

$2,350,000
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118 S Hanley Road Clayton

118 S HANLEY ROAD CLAYTON, Clayton, MO
Property

Retail

3,611 SF
For Sale

$2,250,000
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14 South Bemiston Ave.

14 South Bemiston Ave., Clayton, MO
Property

Retail

1,330 SF
Availability

1 Space

1,330 SF
For Lease

$30.00/SF/YR
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10 North Hanley Road

10 North Hanley Road, Clayton, MO
Property

Office

33,000 SF
Year Built

1963
For Sale Contact for pricing
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Clarendale Clayton

7651 Clayton Rd, Clayton, MO
Property

Retail

1,837 SF
Availability

1 Space

1,837 SF
Year Built

2020
For Lease

$30.00/SF/YR
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6369 Clayton Road Clayton

6369 Clayton Road Clayton, Clayton, MO
Property

Retail

6,200 SF
Availability

1 Space

6,200 SF
For Lease Contact for pricing
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Midvale Building

112 S Hanley Rd Clayton Missouri 63105, Clayton, MO
Property

Office

3,100 SF
Availability

1 Space

3,100 SF
For Lease

$29.50/SF/YR
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Demun Pointe

6541 Clayton Rd, Clayton, MO
Property

Retail

2,560 SF
Availability

1 Space

2,560 SF
For Lease Contact for pricing
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16 North Central Ave

16 N Central Ave, Clayton, Saint Louis, MO
Property

Retail

2,400 SF
Availability

1 Space

2,400 SF
Year Built

1953
For Lease

$30.00/SF/YR
View Details (opens in new window)

Frequently Asked Questions

Commercial real estate is a broad category that includes a high variety of space types designed to meet the needs of various industries of the local economy and their specialized subsectors, as presented in our real estate 101 guide to types of commercial real estate. However, there are three main categories that you are most likely to come across: office, retail, and industrial space.

Modern office space is typically organized over large floor plates bound by high ceilings and large windows for an abundance of natural light and is located in transit-oriented developments with good access to multiple modes of transportation, so as to facilitate employee commute. The Clayton commercial real estate market incorporates 4,796,657 square feet of office space across 31 buildings.

Office buildings can also accommodate coworking spaces, which are shared office options that typically cater to the needs of small, startup businesses that require flexible workspaces, a concentration of amenities, and services that can be accessed on an occasional or short-term basis. In Clayton, the coworking segment of the commercial real estate market incorporates about 400 square feet.
Retail space includes shopping malls, department stores, street retail, or specialty stores dedicated to a narrow range of products. Such properties are typically located in high foot-traffic and/or car traffic areas, to facilitate customer access. The Clayton commercial real estate market includes 48,875 square feet of retail space in a variety of settings.
Industrial property most often serves businesses operating in manufacturing or logistics and generally consists of large open spaces located within good access to roads, railways, freight airports or regional water ports. Industrial space listings can include warehouses, manufacturing plants, distribution centers, flexible industrial space, or even data center facilities.

The listing inventory in Clayton incorporates commercial real estate for lease and for sale of almost all property types and subtypes. However, you’ll find some categories offer more rental or investment opportunities than others.

The largest share of commercial real estate space for lease in Clayton is represented by Office space, which accounts for 898,581 square feet of available listings. Retail space available in Clayton adds up to 19,686 square feet.

Meanwhile, most of the listings of commercial property for sale in Clayton are in the Office category.

The price of renting or buying commercial real estate is influenced by a variety of factors, including: the property type (for example, office space is priced higher than other property types in most locations); the condition and asset class rating (property rated class A or above will typically command a higher price than lower grade classifications); the quality or the development potential of the property location; whether or not there is high demand for the type of commercial asset in question; and what the state of supply is relative to demand.

The average rent for commercial real estate space listed for lease in Clayton is $30.31 per square foot. However, this value does not offer enough perspective on its own, as you will find significant variation in prices across property types, property classes, and location, as well as other impacting factors. For instance, rent per square foot of office space in Clayton can vary greatly depending on the rating of the property from Class A to Class C, as well as across the city depending on the location of the asset.

Whether you are looking for commercial real estate for lease or commercial property for sale, the best choice of location depends on the factors that are most relevant to your business strategy. A good thing to look for at the start, however, is the areas of the city that have the highest concentration of your preferred type of property, as these areas are generally well connected to the amenities and points of interest that are most relevant to each property type.

As such, there are several areas that you could consider to be the best location for commercial real estate in Clayton, depending on the property type you are interested in.

Select your preferred property type from the search filters menu at the top of the search page and then navigate the interactive map for a better view of commercial real estate availability in the locations most suited to your needs.

Regardless of whether buying or leasing commercial space is a new experience for you, there are significant benefits to working with a commercial real estate broker. In addition to saving you time and money, an experienced broker will contribute specialist knowledge of the local market, the property type you need representation for, and will handle negotiations on your behalf in your best interest.

To start, it is important for you to have a good understanding of what kind of broker you need. For instance, there are differences between a tenant broker and a listing broker. Also important at the start is to have a clear idea of what kind of space (or tenant) you are looking for and what (if any) particular needs and requirements you might have. And, while it is good to get a referral, you should interview several brokers to better gauge who you feel would best represent your interests.

CommercialCafe hosts listings from some of the most trusted commercial real estate brokerages in the country. Use the contact form available on each listing page or the contact details for the property representatives to reach out and start your search!

The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself — which itself includes aspects such as location, property class, amenities, and the quality of the property management — to the local market conditions, the state of the local economy, the demand for that particular type of commercial property, and of course the costs of owning and maintaining it relative to what leasing rate or sale price you get from the property. Asking rents in the city went as high as $35 per square foot. In particular, the property type commanding the highest lease rates in Clayton was Office space.

The average size of a commercial property in Clayton depends greatly on the property type and the location — geographical possibilities and zoning allowances have significant influence on how big developers can build. While there are outliers that break height or volume records in the city, we can look at some average sizes by property use:

In Clayton, the average size of an office property is 165,402 square feet.
Retail properties here incorporate an average of 4,888 square feet.

Clayton, St. Louis County, MO Currently Available Listings

Commercial Space for Lease Breakdown

Commercial real estate listings for rent in Clayton currently add up to 977,950 square feet. The market offers 29 active office listing(s), which amount to 958,264 square feet and account for 76% of commercial spaces on the market. Local retail availability includes 19,686 square feet across 9 retail space(s).

Property Type	Count of Listings	Total SF
Office	29	958,264
Retail	9	19,686

Commercial Space for Sale Breakdown

What’s more, if you are interested in making an investment in the local market, you can also find commercial real estate for sale in Clayton, St. Louis County, MO. Currently, there is 97,019 square feet of commercial property for sale here , which includes 2 office building(s) for sale , 2 retail investment opportunity listing(s) .

Property Type	Count of Listings	Total SF
Office	2	67,139
Retail	2	10,811
Other	2	19,069

Clayton, St. Louis County, MO Commercial Real Estate for Lease and Sale

Frequently Asked Questions

What are the different types of commercial real estate?

What types of commercial real estate are available in Clayton, MO?

What factors affect the price of commercial real estate in Clayton, MO?

What is the average rent for commercial space in Clayton, MO?

What are the best areas for commercial real estate in Clayton, MO?

How do I find a good commercial real estate broker?

What is the most profitable commercial real estate?

What is the average size of a commercial property in Clayton, MO?

Clayton, St. Louis County, MO Currently Available Listings

Commercial Space for Lease Breakdown

Commercial Space for Sale Breakdown

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