Saint Charles, MO Commercial Real Estate for Lease and Sale

Explore 126 listings of Saint Charles commercial real estate to find the best space for your business.

Zumbehl Commons

1950 Zumbehl Road, St. Charles, MO
Property

Retail

119,682 SF
Availability

2 Spaces

3,521 SF
For Lease Contact for pricing
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3613 Mueller Road

3613 Mueller Road, St. Charles, MO
Property

Industrial

71,930 SF
Availability

1 Space

65,800 SF
Year Built

1975
For Lease

$9.50/SF/YR
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SSM Health Medical Buildings 1 & 2

330 1st Capitol Drive, St. Charles, MO
Property

Office

81,400 SF
Availability

9 Spaces

15,188 SF
Year Built

1987
For Lease

$24.50 - $28.00/SF/YR
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Streets of St. Charles - 1450 Beale Street

1450 Beale Street, St. Charles, MO
Property

Office

60,000 SF
Availability

1 Space

4,768 SF
Year Built

2018
For Lease

$33.00/SF/YR
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Office Coworking Retail Industrial

Office Retail Industrial Land
Wolfrum Crossing 1041-1057

1041 - 1057 Wolfrum Rd , Weldon Spring, MO
Property

Retail

26,396 SF
Availability

3 Spaces

6,667 SF
Year Built

2000
For Lease Contact for pricing
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3817-3841 Millstone Parkway

3817-3841 Millstone Parkway, Saint Charles, MO
Property

Industrial

130,000 SF
Availability

1 Space

86,800 SF
For Lease

$5.95 - $6.75/SF/YR
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1000 Technology Drive

1000 Technology Drive, Weldon Spring, O'Fallon, MO
Property

Office

518,601 SF
Availability

2 Spaces

126,000 SF
Year Built

2002
For Lease Contact for pricing
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Wolfrum Crossing

1005 - 1037 Wolfrum Rd , Cottleville, Weldon Spring, MO
Property

Retail

24,665 SF
Availability

5 Spaces

9,047 SF
Year Built

2000
For Lease Contact for pricing
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Streets of St. Charles - 1520 South 5th Street

1520 South 5th Street, St. Charles, MO
Property

Office

100,633 SF
Availability

6 Spaces

11,728 SF
Year Built

2011
For Lease

$28.00 - $29.00/SF/YR
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4223-4241 N St Peters Pkwy St Peters

4223-4241 N St Peters Pkwy St Peters, St. Peters, MO
Property

Retail

11,830 SF
Availability

2 Spaces

2,526 SF
For Lease

$14.00/SF/YR
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Centre Pointe Shopping Center

3603 North Saint Peters Parkway, St. Peters, MO
Property

Retail

28,243 SF
Availability

6 Spaces

30,452 SF
Year Built

1983
For Lease

$18.00 - $20.00/SF/YR
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The Oak Creek Center

4045 N St Peters Pkwy, St. Peters, MO
Property

Retail

18,256 SF
Availability

1 Space

3,500 SF
Year Built

1996
For Lease

$16.00/SF/YR
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University Commons

1900 First Capitol Drive, St. Charles, MO
Property

Retail

106,949 SF
Availability

2 Spaces

3,237 SF
For Lease Contact for pricing
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1600 Heritage Landing

1600 Heritage Landing, St. Charles, MO
Property

Office

62,898 SF
Availability

8 Spaces

16,316 SF
Year Built

1980
For Lease

$14.00 - $16.00/SF/YR
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3861 Fountain Lakes Pkwy East

3861 Fountain Lakes Pkwy East, St. Charles, MO
Property

Industrial

120,120 SF
Availability

1 Space

20,000 SF
Year Built

2000
For Lease Contact for pricing
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Three Flags Business Center

1360 South 5th Street, St. Charles, MO
Property

Office

61,754 SF
Availability

7 Spaces

5,831 SF
Year Built

1972
For Lease Contact for pricing
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Streets of St. Charles

1450 Beale St., Saint Charles, MO
Property

Office

36,419 SF
Availability

2 Spaces

36,419 SF
Year Built

2019
For Lease Contact for pricing
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Plaza 94

48 Plaza 94, St. Peters, MO
Property

Retail

66,555 SF
Availability

3 Spaces

4,960 SF
For Lease Contact for pricing
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2700 South Saint Peters Parkway

2700 South Saint Peters Parkway, St. Peters, MO
Property

Office

5,876 SF
Availability

1 Space

5,876 SF
For Lease

$14.00/SF/YR
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Proposed Office Building For Lease

5770 Mexico Rd, City Center Park, St. Peters, MO
Property

Other
Availability

1 Space

13,000 SF
For Lease Contact for pricing
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450 Technology Dr

450 Technology Dr, Weldon Spring, MO
Property

Industrial

76,500 SF
Availability

1 Space

76,500 SF
For Lease Contact for pricing
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1.21 AC Available for Build-to-Suit

Bluestone Dr, St. Charles, MO
Property

Other
Availability

1 Space

1.21 Acre
For Lease Contact for pricing
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Fountain Lakes I

3651 New Town Blvd, St. Charles, MO
Property

Industrial

175,210 SF
Availability

2 Spaces

117,804 SF
Year Built

1999
For Lease Contact for pricing
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The Commons
The Commons
3324 Rue Royale Street, Saint Charles, MO
Services

Virtual Office

Open Workspace

Event Space

Meeting Room

Private Office

Dedicated Desk
Amenities

Catering

Complimentary coffee & tea

Free water

High-speed wifi

Parking

Printer

Privacy booths

Projector

Receptionist/Secretarial services

TV/Monitor
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119 South Main Street
OPO Startups
119 South Main Street, Saint Charles, MO
Services

Open Workspace

Event Space

Meeting Room

Private Office

Dedicated Desk
Amenities

Catering

Cleaning services

Complimentary coffee & tea

High-speed internet

High-speed wifi

Office furniture

Parking

Podcast room

Snacks

TV/Monitor
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2722 South Saint Peters Parkway
The Heritage Small Business Hub
2722 South Saint Peters Parkway, St. Peters, MO
Services

Open Workspace

Event Space

Meeting Room

Private Office
Amenities

Complimentary coffee & tea

Free water

High-speed wifi

Receptionist/Secretarial services

TV/Monitor

Utilities included

White boards
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5377 Highway N
Cottleville Synergy Center
5377 Highway N, Saint Charles, MO
Services

Event Space

Meeting Room

Private Office
Amenities

Cleaning services

Complimentary coffee & tea

Free water

High-speed wifi

Kitchen

Mail services

Parking

Receptionist/Secretarial services

TV/Monitor

Utilities included
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1001-1047 South Duchesne Drive

1001-1047 South Duchesne Drive, Saint Charles, MO
Property

Retail

19,160 SF
Availability

3 Spaces

4,000 SF
Year Built

1978
For Lease

$11.00/SF/YR
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Weldon Spring Center

1030-1120 Wolfrum, Weldon Spring, MO
Property

Retail

51,474 SF
Availability

4 Spaces

16,792 SF
For Lease

$16.00/SF/YR
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South Ridge Shoppes

Highway N & Orf Road, Cottleville, Lake St. Louis, MO
Property

VacantLand

7.75 Acre
For Sale Contact for pricing
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2050 S Old Highway 94

2050 S Old Highway 94, Saint Charles, MO
Property

Office

3,411 SF
Availability

1 Space

3,411 SF
Year Built

1980
For Lease

$13.50/SF/YR
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6120-6140 Mid Rivers Mall Dr

6120-6140 Mid Rivers Mall Drive, St Peters, MO
Property

Retail

19,600 SF
Availability Contact for availability

For Lease Contact for pricing
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N Hwy 94

N Hwy 94, St. Charles, MO
Property

VacantLand

4.91 Acre
For Sale Contact for pricing
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620 S 5th St

620 S 5th St, Saint Charles, MO
Property

Retail

2,952 SF
Availability

1 Space

2,952 SF
Year Built

2002
For Lease

$95,000.00/YR
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Walsh Ct.

Walsh Ct., St. Charles, MO
Property

VacantLand

1.38 Acre
For Sale

$175,000
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3740 West Clay Street

3740 W Clay St, Saint Charles, MO
Property

VacantLand

0.46 Acre
Year Built

1981
For Sale

$325,000
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2795 McClay Rd.

2795 McClay Rd, Saint Charles, MO
Property

VacantLand

0.55 Acre
For Sale

$50,000
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Hwy. N & Merz Farm Lane Lot A

Hwy. N & Merz Farm Lane, Cottleville, Dardenne Prairie, MO
Property

VacantLand

2.27 Acre
For Sale Contact for pricing
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10001 Cottleville Trails Drive

10001 Cottleville Trails Drive, Cottleville, MO
Property

VacantLand

2.5 Acre
For Sale

$2,178,000
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Chesterfield Blue Valley Lot 1D

Olive Street & Chesterfield Airport Road, Howell Island Conservation Area, Chesterfield, MO
Property

VacantLand

1.36 Acre
For Sale Contact for pricing
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SouthPointe

350 Hemsath Rd, Saint Charles, MO
Property

VacantLand

13 Acre
For Sale Contact for pricing
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213 N Main Street

213 N Main St, Saint Charles, MO
Property

Retail

5,203 SF
Availability

1 Space

3,000 SF
Year Built

1890
For Lease

$19.00/SF/YR
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301 Little Hills Expy

301 Little Hills Expy, Saint Charles, MO
Property

Retail

2,895 SF
Availability

1 Space

2,895 SF
Year Built

2005
For Lease

$10,417.00/MO
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504 Droste St.

504 Droste St., Saint Charles, MO
Property

VacantLand

0.5 Acre
For Sale

$50,000
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Mexico Road & Executive Drive (1.42 AC)

Mexico Rd & St Peters Centre Blvd, City Center Park, St. Peters, MO
Property

Other
For Sale

$371,131.2
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SE Corner of Harry S Truman Blvd & Point West Blvd.

SE Corner of Harry S Truman Blvd & Point West Blvd. , Saint Charles, MO
Property

VacantLand

3.5 Acre
For Sale Contact for pricing
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1335 Charlestown Industrial Drive

1335 Charlestown Industrial Dr, Saint Charles, MO
Property

Industrial

7,150 SF
Year Built

1981
For Sale

$850,000
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Land - St. Charles, MO - 2.66 Acres

0 370 & Elm Street , Saint Charles, MO
Property

Other

2.66 Acre
For Sale Contact for pricing
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Hwy. N & Merz Farm Lane Lot C

Hwy. N & Merz Farm Lane, Cottleville, Dardenne Prairie, MO
Property

VacantLand

2.55 Acre
For Sale Contact for pricing
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620 SOUTH FIFTH ST.

620 SOUTH FIFTH ST. , Saint Charles, MO
Property

Retail

2,952 SF
For Sale

$1,200,000
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Blackstone Center

3899 Veterans Memorial Pkwy, Saint Peters, MO
Property

Retail

25,906 SF
Availability

4 Spaces

6,262 SF
Year Built

1985
For Lease Contact for pricing
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3527-3543 North Highway 94

3527-3543 North Highway 94, Saint Charles, MO
Property

VacantLand

2.59 Acre
For Sale

$925,000
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Frequently Asked Questions

Commercial real estate is a broad category that includes a high variety of space types designed to meet the needs of various industries of the local economy and their specialized subsectors, as presented in our real estate 101 guide to types of commercial real estate. However, there are three main categories that you are most likely to come across: office, retail, and industrial space.

Modern office space is typically organized over large floor plates bound by high ceilings and large windows for an abundance of natural light and is located in transit-oriented developments with good access to multiple modes of transportation, so as to facilitate employee commute. The Saint Charles commercial real estate market incorporates 1,067,496 square feet of office space across 28 buildings.

Office buildings can also accommodate coworking spaces, which are shared office options that typically cater to the needs of small, startup businesses that require flexible workspaces, a concentration of amenities, and services that can be accessed on an occasional or short-term basis. In Saint Charles, the coworking segment of the commercial real estate market incorporates about 948 square feet.
Retail space includes shopping malls, department stores, street retail, or specialty stores dedicated to a narrow range of products. Such properties are typically located in high foot-traffic and/or car traffic areas, to facilitate customer access. The Saint Charles commercial real estate market includes 1,315,633 square feet of retail space in a variety of settings.
Industrial property most often serves businesses operating in manufacturing or logistics and generally consists of large open spaces located within good access to roads, railways, freight airports or regional water ports. Industrial space listings can include warehouses, manufacturing plants, distribution centers, flexible industrial space, or even data center facilities. Across the Saint Charles market, there is a total of 723,525 square feet of industrial property.

The listing inventory in Saint Charles incorporates commercial real estate for lease and for sale of almost all property types and subtypes. However, you’ll find some categories offer more rental or investment opportunities than others.

The largest share of commercial real estate space for lease in Saint Charles is represented by Industrial space, which accounts for 407,939 square feet of available listings. Office space available in Saint Charles adds up to 347,109 square feet.

Meanwhile, most of the listings of commercial property for sale in Saint Charles are in the Retail category.

The price of renting or buying commercial real estate is influenced by a variety of factors, including: the property type (for example, office space is priced higher than other property types in most locations); the condition and asset class rating (property rated class A or above will typically command a higher price than lower grade classifications); the quality or the development potential of the property location; whether or not there is high demand for the type of commercial asset in question; and what the state of supply is relative to demand.

The average rent for commercial real estate space listed for lease in Saint Charles is $14.79 per square foot. However, this value does not offer enough perspective on its own, as you will find significant variation in prices across property types, property classes, and location, as well as other impacting factors. For instance, rent per square foot of office space in Saint Charles can vary greatly depending on the rating of the property from Class A to Class C, as well as across the city depending on the location of the asset.

Whether you are looking for commercial real estate for lease or commercial property for sale, the best choice of location depends on the factors that are most relevant to your business strategy. A good thing to look for at the start, however, is the areas of the city that have the highest concentration of your preferred type of property, as these areas are generally well connected to the amenities and points of interest that are most relevant to each property type.

As such, there are several areas that you could consider to be the best location for commercial real estate in Saint Charles, depending on the property type you are interested in. The highest concentration of commercial space listings of any kind in Saint Charles is in the City Center Park neighborhood. But if we look at each commercial property type, we find that for office space, the best location is the City Center Park area.

Select your preferred property type from the search filters menu at the top of the search page and then navigate the interactive map for a better view of commercial real estate availability in the locations most suited to your needs.

Regardless of whether buying or leasing commercial space is a new experience for you, there are significant benefits to working with a commercial real estate broker. In addition to saving you time and money, an experienced broker will contribute specialist knowledge of the local market, the property type you need representation for, and will handle negotiations on your behalf in your best interest.

To start, it is important for you to have a good understanding of what kind of broker you need. For instance, there are differences between a tenant broker and a listing broker. Also important at the start is to have a clear idea of what kind of space (or tenant) you are looking for and what (if any) particular needs and requirements you might have. And, while it is good to get a referral, you should interview several brokers to better gauge who you feel would best represent your interests.

CommercialCafe hosts listings from some of the most trusted commercial real estate brokerages in the country. Use the contact form available on each listing page or the contact details for the property representatives to reach out and start your search!

The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself — which itself includes aspects such as location, property class, amenities, and the quality of the property management — to the local market conditions, the state of the local economy, the demand for that particular type of commercial property, and of course the costs of owning and maintaining it relative to what leasing rate or sale price you get from the property. Asking rents in the city went as high as $25 per square foot. In particular, the property type commanding the highest lease rates in Saint Charles was Office space.

The average size of a commercial property in Saint Charles depends greatly on the property type and the location — geographical possibilities and zoning allowances have significant influence on how big developers can build. While there are outliers that break height or volume records in the city, we can look at some average sizes by property use:

In Saint Charles, the average size of an office property is 59,306 square feet.
Retail properties here incorporate an average of 41,114 square feet.
Industrial space in Saint Charles is in buildings that are, on average 65,775 square feet in size.

Saint Charles, MO Currently Available Listings

Commercial Space for Lease Breakdown

Commercial real estate listings for rent in Saint Charles currently add up to 2,317,843 square feet. The market offers 26 active office listing(s), which amount to 347,109 square feet and account for 37% of commercial spaces on the market. Local retail availability includes 230,622 square feet across 28 retail space(s). Industrial space for rent opportunities in Saint Charles amount to 400,339 square feet across a total of 8 warehouse and other industrial listing(s).

Property Type	Count of Listings	Total SF
Office	26	347,109
Retail	28	230,622
Industrial	8	400,339
Other	8	1,339,773

Commercial Space for Sale Breakdown

What’s more, if you are interested in making an investment in the local market, you can also find commercial real estate for sale in Saint Charles, MO. Currently, there is 146,281 square feet of commercial property for sale here , which includes 2 office building(s) for sale , 7 retail investment opportunity listing(s) , and 2 listing(s) of industrial real estate property for sale .

Property Type	Count of Listings	Total SF
Office	2	18,800
Retail	7	89,834
Industrial	2	37,515
Other	44	132

Saint Charles, MO Commercial Real Estate for Lease and Sale

Frequently Asked Questions

What are the different types of commercial real estate?

What types of commercial real estate are available in Saint Charles, MO?

What factors affect the price of commercial real estate in Saint Charles, MO?

What is the average rent for commercial space in Saint Charles, MO?

What are the best areas for commercial real estate in Saint Charles, MO?

How do I find a good commercial real estate broker?

What is the most profitable commercial real estate?

What is the average size of a commercial property in Saint Charles, MO?

Saint Charles, MO Currently Available Listings

Commercial Space for Lease Breakdown

Commercial Space for Sale Breakdown

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