Saint Louis, MO Commercial Real Estate for Lease and Sale

Explore 330 listings of Saint Louis commercial real estate to find the best space for your business.

S. Grand Mixed Use Building w/ Turnkey Restaurant

3159 S Grand Blvd, Tower Grove South, Saint Louis, MO
Property

Mixed Use

7,208 SF
Year Built

1909
For Sale

$795,000
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500 North Broadway

500 North Broadway, Downtown Saint Louis, St. Louis, MO
Property

Office

280,000 SF
Availability

7 Spaces

72,370 SF
Year Built

1969
For Lease

$17.50 - $18.50/SF/YR
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3224 South Kingshighway Blvd

3224 South Kingshighway Blvd, Tower Grove South, St. Louis, MO
Property

Retail

68,584 SF
Year Built

1920
For Sale

$1,600,000
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The Bavarian Inn

3012 Arsenal Street, Tower Grove East, St. Louis, MO
Property

Mixed Use

4,160 SF
Availability

1 Space

2,080 SF
Year Built

1913
For Lease

$18.00/SF/YR
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Office Coworking Retail Industrial

Office Retail Industrial Land
Hampton Avenue Retail

3511-3525 Hampton Avenue, Lindenwood Park, St. Louis, MO
Property

Retail

17,690 SF
Availability

1 Space

3,000 SF
Year Built

1947
For Lease

$18.00/SF/YR
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2025 Olive St

2025 Olive Street, Downtown West Saint Louis, Saint Louis, MO
Property

Retail

9,349 SF
Availability

1 Space

8,500 SF
Year Built

1955
For Lease Contact for pricing
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4981 Rosalie St

4981 Rosalie St, Mark Twain, Saint Louis, MO
Property

Multi-Family

11,548 SF
Year Built

1928
For Sale

$1,100,000
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Downtown Industrial Site with Outside Storage

1900 Cole Street, Downtown West Saint Louis, St. Louis, MO
Property

Industrial

43,175 SF
Year Built

1890
For Sale

$1,900,000
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Cast Iron Building

712 N 2nd St, Downtown Saint Louis, Saint Louis, MO
Property

Office

20,000 SF
Availability

4 Spaces

11,921 SF
Year Built

1896
For Lease

$12.00/SF/YR
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4550 Gustine Avenue

4550 Gustine Avenue, Dutchtown, St. Louis, MO
Property

Industrial

226,717 SF
Availability

1 Space

91,717 SF
Year Built

1951
For Lease

$3.75/SF/YR
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3133 Cherokee St

3133 Cherokee St, Benton Park West, Saint Louis, MO
Property

Retail

4,950 SF
Year Built

1909
For Sale

$375,000
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Security Building

319 N 4th St, Downtown Saint Louis, St. Louis, MO
Property

Office

147,775 SF
Availability

13 Spaces

48,868 SF
Year Built

1882
For Lease

$12.50/SF/YR
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4330 S Broadway (29,000sf Warehouse/Retail)

4330 S Broadway, Mount Pleasant, Saint Louis, MO
Property

Industrial

29,390 SF
Year Built

1968
For Sale

$1,790,000/SF
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Metropolitan Flats Retail

4561 Forest Park Avenue, Central West End Saint Louis, St. Louis, MO
Property

Retail

5,477 SF
Availability

1 Space

5,477 SF
Year Built

2005
For Lease Contact for pricing
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Southside Tower

3606 Gravois Ave, Tower Grove South, Saint Louis, MO
Property

Mixed Use

50,000 SF
Availability

1 Space

1,630 SF
Year Built

1928
For Lease Contact for pricing
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St. Louis Place

200 N. Broadway, Downtown Saint Louis, St. Louis, MO
Property

Office

337,088 SF
Availability

9 Spaces

56,850 SF
Year Built

1983
For Lease

$17.50/SF/YR
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The Nicholas

1500-1506 s. grand St. Louis, The Gate District, St. Louis, MO
Property

Retail

1,245 SF
Availability

1 Space

1,245 SF
For Lease

$28.00/SF/YR
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Class A Office Spaces For Lease in the Heart of Downtown St. Louis

10 S Broadway, Downtown Saint Louis, St. Louis, MO
Property

Office
Availability

1 Space

17,570 SF
Year Built

1971
For Lease Contact for pricing
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1335 Convention Plaza

1335 Convention Plaza, Downtown West Saint Louis, St. Louis, MO
Property

Industrial

28,500 SF
Availability

1 Space

28,500 SF
For Lease

$3.00/SF/YR
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Downtown West Restaurant Space

1818 Washington Ave, Downtown West Saint Louis, Saint Louis, MO
Property

Retail

18,591 SF
Availability

1 Space

3,831 SF
Year Built

1924
For Lease

$18.00/SF/YR
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Kingshighway & Arsenal - Development Site

3108 South Kingshighway Boulevard, Tower Grove South, St. Louis, MO
Property

Retail

1,647 SF
Year Built

1997
For Sale

$499,000
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Farmer's Merchant

3550-3552 Gravois Ave, Gravois Park, Saint Louis, MO
Property

Retail

28,935 SF
Availability

2 Spaces

2,005 SF
Year Built

1914
For Lease

$10.00/SF/YR
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Southtown Plaza

4600 - 4610 Chippewa St , North Hampton, Saint Louis, MO
Property

Retail

44,970 SF
Availability

5 Spaces

13,400 SF
Year Built

1986
For Lease Contact for pricing
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The 22

2200 Locust Street, Downtown West Saint Louis, St. Louis, MO
Property

Mixed Use

38,750 SF
Availability

1 Space

3,420 SF
Year Built

1916
For Lease

$18.00/SF/YR
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6414 Hampton Ave

6414 Hampton Ave, Princeton Heights, Saint Louis, MO
Property

Mixed Use

8,000 SF
Availability

4 Spaces

1,000 SF
Year Built

1953
For Lease

$450.00/MO
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1928 Locust Street

1928 Locust Street, Downtown West Saint Louis, St. Louis, MO
Property

Office

38,072 SF
Availability

1 Space

38,072 SF
For Lease

$15.00/SF/YR
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Moolah Theatre/Lounge & Bowling Alley

3821 Lindell Boulevard, Covenant Blu - Grand Center, St. Louis, MO
Property

Retail

116,512 SF
Availability

1 Space

23,000 SF
Year Built

1904
For Lease Contact for pricing
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Tower Grove South - Adaptive Reuse Opportunity

4101-4125 Humphrey Street, Tower Grove South, St. Louis, MO
Property

Special Purpose

16,988 SF
Year Built

1925
For Sale

$1,999,000
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3000-3008 S Jefferson Ave

3000-3008 S Jefferson Ave, Benton Park, Saint Louis, MO
Property

Office

12,736 SF
Availability

1 Space

135 SF
Year Built

1900
For Lease

$44.00/SF/YR
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Kingshighway Development Site

3500 South Kingshighway Boulevard, Tower Grove South, St. Louis, MO
Property

Retail

11,674 SF
Year Built

1952
For Sale

$1,499,000
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2345 Pine Street

2345 Pine Street, Downtown West Saint Louis, Saint Louis, MO
Property

Office

2,500 SF
Year Built

1961
For Sale Contact Broker
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245 Union Blvd

245 Union Blvd, DeBaliviere Place, Saint Louis, MO
Property

Unassigned

165,661 SF
Availability

1 Space

8,263 SF
Year Built

1918
For Lease Contact for pricing
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3 -11 South Newstead Avenue

3 -11 South Newstead Avenue, Central West End Saint Louis, St. Louis, MO
Property

Office

5,175 SF
Availability

2 Spaces

3,425 SF
Year Built

1905
For Lease

$19.57/SF/YR
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3640 Natural Bridge Ave

3640 Natural Bridge Ave, Jeff Vanderlou, Saint Louis, MO
Property

Mixed Use

61,150 SF
Availability

2 Spaces

4,300 SF
Year Built

1927
For Lease

$12.00 - $14.00/SF/YR
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Grant School Apartments

3009 Pennsylvania Ave, Tower Grove East, Saint Louis, MO
Property

Multi-Family

27,300 SF
Year Built

1905
For Sale

$2,600,000
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2360 Hampton Ave

2360 Hampton Ave, The Hill, St. Louis, MO
Property

Retail

9,881 SF
Availability

1 Space

640 SF
Year Built

1959
For Lease Contact for pricing
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5437 Page Blvd

5437 Page Blvd, Hamilton Heights, Saint Louis, MO
Property

Multi-Family

15,444 SF
Year Built

1908
For Sale

$1,400,000
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Marquette Building

300-314 N Broadway, Downtown Saint Louis, Saint Louis, MO
Property

Mixed Use

194,712 SF
Availability

5 Spaces

45,793 SF
Year Built

1913
For Lease Contact for pricing
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Bank of America Tower

100 North Broadway, Downtown Saint Louis, St. Louis, MO
Property

Office

510,202 SF
Availability

12 Spaces

230,631 SF
Year Built

1974
For Lease

$18.00/SF/YR
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501-519 North Grand Blvd

501 North Grand Blvd, Covenant Blu - Grand Center, St. Louis, MO
Property

Office

49,754 SF
Availability

2 Spaces

9,535 SF
Year Built

1940
For Lease

$24.50/SF/YR
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Ludwig Building Downtown Office and Retail

1006 Olive Street, Downtown Saint Louis, St. Louis, MO
Property

Mixed Use

44,236 SF
Availability

2 Spaces

3,947 SF
Year Built

1905
For Lease

$12.50/SF/YR
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4410 Hunt Avenue

4410 Hunt Avenue, Forest Park South East, St. Louis, MO
Property

Industrial

57,850 SF
Availability

1 Space

25,000 SF
Year Built

1928
For Lease

$1.25/SF/MO
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Gateway Tower

South Memorial Drive, Downtown Saint Louis, St. Louis, MO
Property

Office

213,228 SF
Availability

12 Spaces

98,117 SF
For Lease

$16.75/SF/YR
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Industrial Showroom

8393 Hall Street, Baden, St. Louis, MO
Property

Industrial

12,500 SF
Year Built

1999
For Sale

$1,250,000
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2820 Market Street

2820 Market Street, Midtown Saint Louis, St. Louis, MO
Property

Industrial

27,450 SF
Availability

1 Space

27,450 SF
Year Built

1968
For Lease

$5.00/SF/YR
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Cubework St. Louis

601 East Red Bud Avenue, North Riverfront, St. Louis, MO
Property

Industrial

61,118 SF
Availability

3 Spaces

56,000 SF
Year Built

1942
For Lease Contact for pricing
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2800 N Grand Blvd

2800 N Grand Blvd, Jeff Vanderlou, Saint Louis, MO
Property

Mixed Use

48,072 SF
Year Built

1925
For Sale

$920,000
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1610-1612 South Jefferson

1610-1612 South Jefferson Avenue, Lafayette Square, St. Louis, MO
Property

Multi-Family

3,688 SF
For Sale

$450,000
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Monkey Building

1430 Washington Avenue, Downtown West Saint Louis, St. Louis, MO
Property

Office

27,045 SF
Availability

4 Spaces

7,719 SF
Year Built

2006
For Lease

$10.00 - $24.00/SF/YR
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Cortex 1 - Office/Lab Space For Lease

4320 Forest Park Ave, Central West End Saint Louis, St. Louis, MO
Property

Office
Availability

1 Space

27,048 SF
For Lease Contact for pricing
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2000-2010 S 8th St (Soulard)

2000 S 8th St, Soulard, Saint Louis, MO
Property

Office

11,868 SF
Year Built

2005
For Sale

$1,499,000
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2233 Delmar Blvd

2219-2233 Delmar Blvd, Downtown West Saint Louis, Saint Louis, MO
Property

Industrial

92,000 SF
Availability

1 Space

92,000 SF
For Lease

$3.25 - $4.25/SF/YR
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Frequently Asked Questions

Commercial real estate is a broad category that includes a high variety of space types designed to meet the needs of various industries of the local economy and their specialized subsectors, as presented in our real estate 101 guide to types of commercial real estate. However, there are three main categories that you are most likely to come across: office, retail, and industrial space.

Modern office space is typically organized over large floor plates bound by high ceilings and large windows for an abundance of natural light and is located in transit-oriented developments with good access to multiple modes of transportation, so as to facilitate employee commute. The Saint Louis commercial real estate market incorporates 7,106,355 square feet of office space across 111 buildings.

Office buildings can also accommodate coworking spaces, which are shared office options that typically cater to the needs of small, startup businesses that require flexible workspaces, a concentration of amenities, and services that can be accessed on an occasional or short-term basis.
Retail space includes shopping malls, department stores, street retail, or specialty stores dedicated to a narrow range of products. Such properties are typically located in high foot-traffic and/or car traffic areas, to facilitate customer access. The Saint Louis commercial real estate market includes 2,464,139 square feet of retail space in a variety of settings.
Industrial property most often serves businesses operating in manufacturing or logistics and generally consists of large open spaces located within good access to roads, railways, freight airports or regional water ports. Industrial space listings can include warehouses, manufacturing plants, distribution centers, flexible industrial space, or even data center facilities. Across the Saint Louis market, there is a total of 4,910,131 square feet of industrial property.

The listing inventory in Saint Louis incorporates commercial real estate for lease and for sale of almost all property types and subtypes. However, you’ll find some categories offer more rental or investment opportunities than others.

The largest share of commercial real estate space for lease in Saint Louis is represented by Office space, which accounts for 2,700,085 square feet of available listings. Industrial space available in Saint Louis adds up to 2,210,515 square feet.

Meanwhile, most of the listings of commercial property for sale in Saint Louis are in the Industrial category.

The price of renting or buying commercial real estate is influenced by a variety of factors, including: the property type (for example, office space is priced higher than other property types in most locations); the condition and asset class rating (property rated class A or above will typically command a higher price than lower grade classifications); the quality or the development potential of the property location; whether or not there is high demand for the type of commercial asset in question; and what the state of supply is relative to demand.

The average rent for commercial real estate space listed for lease in Saint Louis is $16.13 per square foot. However, this value does not offer enough perspective on its own, as you will find significant variation in prices across property types, property classes, and location, as well as other impacting factors. For instance, rent per square foot of office space in Saint Louis can vary greatly depending on the rating of the property from Class A to Class C, as well as across the city depending on the location of the asset. What’s more, each commercial property type makes its own rent market: while the average rent for office space rested at $24.6 per square foot, industrial space in Saint Louis saw average rents of $4.89 per square foot.

Whether you are looking for commercial real estate for lease or commercial property for sale, the best choice of location depends on the factors that are most relevant to your business strategy. A good thing to look for at the start, however, is the areas of the city that have the highest concentration of your preferred type of property, as these areas are generally well connected to the amenities and points of interest that are most relevant to each property type.

As such, there are several areas that you could consider to be the best location for commercial real estate in Saint Louis, depending on the property type you are interested in. The highest concentration of commercial space listings of any kind in Saint Louis is in the Downtown Saint Louis neighborhood. But if we look at each commercial property type, we find that for office space, the best location is the Downtown Saint Louis area.

Meanwhile, retail space opportunities are most abundant in the Downtown Saint Louis submarket. Alternatively, if you are looking for warehouse or other industrial space, consider looking at listings in North Riverfront.

Select your preferred property type from the search filters menu at the top of the search page and then navigate the interactive map for a better view of commercial real estate availability in the locations most suited to your needs.

Regardless of whether buying or leasing commercial space is a new experience for you, there are significant benefits to working with a commercial real estate broker. In addition to saving you time and money, an experienced broker will contribute specialist knowledge of the local market, the property type you need representation for, and will handle negotiations on your behalf in your best interest.

To start, it is important for you to have a good understanding of what kind of broker you need. For instance, there are differences between a tenant broker and a listing broker. Also important at the start is to have a clear idea of what kind of space (or tenant) you are looking for and what (if any) particular needs and requirements you might have. And, while it is good to get a referral, you should interview several brokers to better gauge who you feel would best represent your interests.

CommercialCafe hosts listings from some of the most trusted commercial real estate brokerages in the country. Use the contact form available on each listing page or the contact details for the property representatives to reach out and start your search!

The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself — which itself includes aspects such as location, property class, amenities, and the quality of the property management — to the local market conditions, the state of the local economy, the demand for that particular type of commercial property, and of course the costs of owning and maintaining it relative to what leasing rate or sale price you get from the property. Asking rents in the city went as high as $44.65 per square foot. In particular, the property type commanding the highest lease rates in Saint Louis was Office space.

Conversely, the highest sale price last year was $9,700,000 that is located at 8640 Evans Avenue.

The average size of a commercial property in Saint Louis depends greatly on the property type and the location — geographical possibilities and zoning allowances have significant influence on how big developers can build. While there are outliers that break height or volume records in the city, we can look at some average sizes by property use:

In Saint Louis, the average size of an office property is 78,092 square feet.
Retail properties here incorporate an average of 28,324 square feet.
Industrial space in Saint Louis is in buildings that are, on average 77,939 square feet in size.

Saint Louis, MO Currently Available Listings

Commercial Space for Lease Breakdown

Commercial real estate listings for rent in Saint Louis currently add up to 6,267,814 square feet. The market offers 89 active office listing(s), which amount to 2,704,931 square feet and account for 43% of commercial spaces on the market. Local retail availability includes 743,454 square feet across 67 retail space(s). Industrial space for rent opportunities in Saint Louis amount to 2,290,153 square feet across a total of 35 warehouse and other industrial listing(s).

Property Type	Count of Listings	Total SF
Office	89	2,704,931
Retail	67	743,454
Industrial	35	2,290,153
Other	12	529,276

Commercial Space for Sale Breakdown

What’s more, if you are interested in making an investment in the local market, you can also find commercial real estate for sale in Saint Louis, MO. Currently, there is 3,079,793 square feet of commercial property for sale here , which includes 27 office building(s) for sale , 30 retail investment opportunity listing(s) , and 34 listing(s) of industrial real estate property for sale .

Property Type	Count of Listings	Total SF
Office	27	666,791
Retail	30	273,263
Industrial	34	1,782,823
Other	30	356,916

Saint Louis, MO Commercial Real Estate for Lease and Sale

Frequently Asked Questions

What are the different types of commercial real estate?

What types of commercial real estate are available in Saint Louis, MO?

What factors affect the price of commercial real estate in Saint Louis, MO?

What is the average rent for commercial space in Saint Louis, MO?

What are the best areas for commercial real estate in Saint Louis, MO?

How do I find a good commercial real estate broker?

What is the most profitable commercial real estate?

What is the average size of a commercial property in Saint Louis, MO?

Saint Louis, MO Currently Available Listings

Commercial Space for Lease Breakdown

Commercial Space for Sale Breakdown

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