Durham, NC Commercial Real Estate for Lease and Sale

Explore 274 listings of Durham commercial real estate to find the best space for your business.

1955 West Cornwallis Road

1955 West Cornwallis Road, Cameron Woods, Durham, NC
Property

VacantLand

22,158 SF
Year Built

1975
For Sale

$4,500,000
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Quadrangle III

6350 Quadrangle Drive, The Landing at Southpoint, Chapel Hill, NC
Property

Office

56,199 SF
Availability

3 Spaces

21,062 SF
Year Built

1994
For Lease

$28.50/SF/YR
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American Tobacco Campus Sublease

324 Blackwell Street, Downtown Durham, Durham, NC
Property

Office

16,553 SF
Availability

1 Space

7,487 SF
For Lease Contact for pricing
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2510 Meridian

2510 Meridian Parkway, Copper Creek, Durham, NC
Property

Office

64,688 SF
Availability

4 Spaces

39,376 SF
For Lease Contact for pricing
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Office Coworking Retail Industrial

Office Retail Industrial Land
401 E. Chapel Hill Street, 2nd Floor Suite

401 E. Chapel Hill Street, 2nd Floor Suite, Central Park, Durham, NC
Property

Office

3,000 SF
Availability

1 Space

3,000 SF
For Lease Contact for pricing
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Hope Valley Commons

1125 NC Hwy 54, Highgate, Durham, NC
Property

Retail

2,565 SF
Availability

1 Space

2,565 SF
Year Built

2008
For Lease Contact for pricing
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949 Washington Street

949 Washington Street, Duke Park, Durham, NC
Property

Unassigned

37,492 SF
Availability

2 Spaces

37,492 SF
Year Built

1955
For Lease

$41.00/SF/YR
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125 Stallings Road

125 Stallings Road, Grove Park, Durham, NC
Property

VacantLand
For Sale

$1,500,000
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1515 North Pointe Drive

1515 North Pointe Drive, Duke Homestead, Durham, NC
Property

Retail

7,300 SF
Availability

1 Space

7,300 SF
For Lease

$14.00/SF/YR
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Central Park One

5001 S Miami Blvd, Research Triangle Park, Durham, NC
Property

Office

100,660 SF
Availability

6 Spaces

36,291 SF
Year Built

1986
For Lease Contact for pricing
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1671 TW Alexander Drive

1671 TW Alexander Drive, Taylor Estates, Durham, NC
Property

VacantLand
For Sale

$228,000
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2605 Meridian

2605 Meridian Parkway, Copper Creek, Durham, NC
Property

Office

74,071 SF
Availability

3 Spaces

49,387 SF
For Lease Contact for pricing
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4603 Durham-Chapel Hill Blvd

4603 Durham-Chapel Hill Blvd, Westgate Townes, Durham, NC
Property

VacantLand
Availability

1 Space

112,384 SF
For Lease Contact for pricing
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Golden Belt - Blds 2-6

807 E Main Street, Golden Belt, Durham, NC
Property

Office

136,382 SF
Availability

1 Space

1,536 SF
Year Built

2007
For Lease Contact for pricing
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Measurement Building

404 Hunt Street, Central Park, Durham, NC
Property

Office

73,713 SF
Availability

1 Space

4,878 SF
Year Built

2011
For Lease Contact for pricing
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2810 Meridian

2810 Meridian Parkway, Copper Creek, Durham, NC
Property

Office

100,878 SF
Availability

2 Spaces

8,947 SF
For Lease Contact for pricing
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Creekstone Office Park - 4620 Creekstone Drive

4620 Creekstone Drive, Research Triangle Park, Durham, NC
Property

Office

35,391 SF
Availability

2 Spaces

9,597 SF
Year Built

2000
For Lease

$28.50/SF/YR
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Up to 272,937 SF Available at 3508 Tricenter Blvd

3508 Tricenter Blvd, Wynterfield, Durham, NC
Property

Industrial
Availability

1 Space

272,396 SF
Year Built

1989
For Lease Contact for pricing
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1702 N Miami Blvd

1702 N Miami Blvd, Wellons Village, Durham, NC
Property

Retail

1,815 SF
For Sale

$650,000
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10600 Glenwood Avenue

10600 Glenwood Avenue, Ravenstone, Raleigh, NC
Property

VacantLand
For Sale

$1,500,000
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Boxyard RTP

900 Park Offices Drive, Research Triangle Park, Durham, NC
Property

Retail

960 SF
Availability

1 Space

960 SF
For Lease

$3,750.00/MO
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Meridian Corporate Center - 2635 Meridian Pkwy

2635 Meridian Pkwy, Copper Creek, Durham, NC
Property

Office

63,394 SF
Availability

4 Spaces

44,073 SF
Year Built

2000
For Lease

$18.50 - $25.50/SF/YR
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Quadrangle V

6330 Quadrangle Drive, The Landing at Southpoint, Chapel Hill, NC
Property

Office

96,416 SF
Availability

3 Spaces

48,550 SF
Year Built

1995
For Lease Contact for pricing
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3533 Gibson Road

3533 Gibson Road, Amberlynn Valley, Durham, NC
Property

VacantLand
For Sale

$299,000
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5010, 5014 & 5022 Guess Road

5010, 5014 & 5022 Guess Road, Pine Valley, Durham, NC
Property

VacantLand
For Sale

$1,500,000
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Herald-Sun Building

2828 Pickett Road, Cameron Woods, Durham, NC
Property

Office

140,000 SF
Availability

7 Spaces

9,207 SF
Year Built

2018
For Lease

$21.00 - $30.00/SF/YR
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814 Midland Terrace

814 Midland Terrace, Northeast Hills, Durham, NC
Property

VacantLand
Availability

1 Space

20,908 SF
For Lease

$2,200.00/MO
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Meridian Corporate Center - 2700 Meridian Pkwy

2700 Meridian Pkwy, Copper Creek, Durham, NC
Property

Office

51,637 SF
Availability

1 Space

25,952 SF
Year Built

1997
For Lease

$23.50/SF/YR
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Erwin Terrace

2816 Erwin Road, Crest Street, Durham, NC
Property

Retail

64,997 SF
Availability

1 Space

1,716 SF
For Lease

$23.75/SF/YR
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Western Business Park

4307 Western Park Place, Bennet Place, Durham, NC
Property

Office

29,538 SF
Availability

1 Space

164 SF
Year Built

2001
For Lease

$450.00/MO
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Atlas

321 W Corporation St, Old North Durham, Durham, NC
Property

Retail

114,840 SF
Availability

3 Spaces

2,731 SF
Year Built

2020
For Lease

$35.00/SF/YR
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The Kress Building

101 W Main St, Downtown Durham, Durham, NC
Property

Office

49,000 SF
Availability

1 Space

5,153 SF
For Lease Contact for pricing
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300 E. Main St.

300 E. Main St., Downtown Durham, Durham, NC
Property

Office

30,517 SF
Availability

1 Space

5,516 SF
Year Built

1925
For Lease Contact for pricing
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433 W. Main Street

433 W. Main Street, Warehouse District, Durham, NC
Property

Office

16,692 SF
Availability

3 Spaces

13,561 SF
For Lease Contact for pricing
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Venable Center

303 South Roxboro Street, Downtown Durham, Durham, NC
Property

Office

85,886 SF
Availability

2 Spaces

15,998 SF
Year Built

2006
For Lease

$36.50/SF/YR
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Roxboro Road Professional Center

4210 N Roxboro Rd, Summer Meadow, Durham, NC
Property

Office

2,408 SF
Year Built

2004
For Sale

$679,000
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Meridian Corporate Center - 2645 Meridian Pkwy

2645 Meridian Pkwy, Copper Creek, Durham, NC
Property

Office

76,446 SF
Availability

4 Spaces

20,562 SF
Year Built

2017
For Lease

$22.50/SF/YR
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One City Center
WeWork
110 Corcoran Street, Durham, NC
Services

Virtual Office

Open Workspace

Event Space

Meeting Room

Private Office

Dedicated Desk
Amenities

Complimentary coffee & tea

Ethernet

Free water

Game room

High-speed wifi

IT support

Kitchen

Lounge area

Mother’s room

Office supplies
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2505 Meridian

2505 Meridian Parkway, Copper Creek, Durham, NC
Property

Office

42,705 SF
Availability

3 Spaces

11,054 SF
For Lease Contact for pricing
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Bristol Place

4819 Emperor Blvd., Research Triangle Park, Durham, NC
Property

Office

105,410 SF
Availability

5 Spaces

49,463 SF
For Lease

$30.50/SF/YR
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Quadrangle II

6320 Quadrangle Drive, The Landing at Southpoint, Chapel Hill, NC
Property

Office

56,182 SF
Availability

2 Spaces

7,691 SF
Year Built

1988
For Lease Contact for pricing
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Durham Summit I

3414 North Duke Street, Stadium Heights, Durham, NC
Property

Office

57,500 SF
Availability

4 Spaces

37,393 SF
Year Built

1987
For Lease Contact for pricing
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Imperial Center - Carlisle Place

4721 Emperor Blvd, Research Triangle Park, Durham, NC
Property

Office

120,784 SF
Availability

2 Spaces

13,020 SF
Year Built

2007
For Lease

$32.50/SF/YR
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2714 Angier Ave

2714 Angier Ave, Amberlynn Valley, Durham, NC
Property

Other

12,000 SF
Availability

1 Space

17,000 SF
Year Built

2024
For Lease

$1.00/MO
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Downtown Durham Office/Retail Condo

204 Rigsbee Ave, Suite 101, Central Park, Durham, NC
Property

Office

3,944 SF
Year Built

1939
For Sale

$1,450,000
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Research Commons

79 TW Alexander Drive, Research Triangle Park, Durham, NC
Property

Office

422,483 SF
Availability

4 Spaces

52,282 SF
Year Built

1985
For Lease

$27.00/SF/YR
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1502 Old Oxford Road

1502 Old Oxford Road, Falls Lake, Durham, NC
Property

VacantLand
For Sale

$1,777,500
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3430 & 3432 NC-55 Hwy

3430 & 3432 NC-55 Hwy, Abercromby, Durham, NC
Property

VacantLand
For Sale

$575,000
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Central Park Two

5003 S Miami Blvd, Research Triangle Park, Durham, NC
Property

Office

125,018 SF
Availability

3 Spaces

53,938 SF
Year Built

1998
For Lease Contact for pricing
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Westgate II Office Park

3622 Lyckan Pkwy, Chapel Hill Road, Durham, NC
Property

Office

35,160 SF
Availability

2 Spaces

1,947 SF
Year Built

1986
For Lease

$20.00 - $21.00/SF/YR
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3400 Croasdaile Drive

3400 Croasdaile Drive, Croasdaile, Durham, NC
Property

Other

2,166 SF
Availability

1 Space

2,166 SF
For Lease

$3,250.00/MO
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2800 Meridian

2800 Meridian Parkway, Copper Creek, Durham, NC
Property

Office

51,066 SF
Availability

1 Space

3,574 SF
For Lease Contact for pricing
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Frequently Asked Questions

Commercial real estate is a broad category that includes a high variety of space types designed to meet the needs of various industries of the local economy and their specialized subsectors, as presented in our real estate 101 guide to types of commercial real estate. However, there are three main categories that you are most likely to come across: office, retail, and industrial space.

Modern office space is typically organized over large floor plates bound by high ceilings and large windows for an abundance of natural light and is located in transit-oriented developments with good access to multiple modes of transportation, so as to facilitate employee commute. The Durham commercial real estate market incorporates 13,753,909 square feet of office space across 141 buildings.

Office buildings can also accommodate coworking spaces, which are shared office options that typically cater to the needs of small, startup businesses that require flexible workspaces, a concentration of amenities, and services that can be accessed on an occasional or short-term basis.
Retail space includes shopping malls, department stores, street retail, or specialty stores dedicated to a narrow range of products. Such properties are typically located in high foot-traffic and/or car traffic areas, to facilitate customer access. The Durham commercial real estate market includes 2,971,611 square feet of retail space in a variety of settings.
Industrial property most often serves businesses operating in manufacturing or logistics and generally consists of large open spaces located within good access to roads, railways, freight airports or regional water ports. Industrial space listings can include warehouses, manufacturing plants, distribution centers, flexible industrial space, or even data center facilities. Across the Durham market, there is a total of 1,139,003 square feet of industrial property.

The listing inventory in Durham incorporates commercial real estate for lease and for sale of almost all property types and subtypes. However, you’ll find some categories offer more rental or investment opportunities than others.

The largest share of commercial real estate space for lease in Durham is represented by Office space, which accounts for 4,955,848 square feet of available listings. Industrial space available in Durham adds up to 1,498,769 square feet.

Meanwhile, most of the listings of commercial property for sale in Durham are in the Office category.

The price of renting or buying commercial real estate is influenced by a variety of factors, including: the property type (for example, office space is priced higher than other property types in most locations); the condition and asset class rating (property rated class A or above will typically command a higher price than lower grade classifications); the quality or the development potential of the property location; whether or not there is high demand for the type of commercial asset in question; and what the state of supply is relative to demand.

The average rent for commercial real estate space listed for lease in Durham is $26.31 per square foot. However, this value does not offer enough perspective on its own, as you will find significant variation in prices across property types, property classes, and location, as well as other impacting factors. For instance, rent per square foot of office space in Durham can vary greatly depending on the rating of the property from Class A to Class C, as well as across the city depending on the location of the asset.

Whether you are looking for commercial real estate for lease or commercial property for sale, the best choice of location depends on the factors that are most relevant to your business strategy. A good thing to look for at the start, however, is the areas of the city that have the highest concentration of your preferred type of property, as these areas are generally well connected to the amenities and points of interest that are most relevant to each property type.

As such, there are several areas that you could consider to be the best location for commercial real estate in Durham, depending on the property type you are interested in. The highest concentration of commercial space listings of any kind in Durham is in the Research Triangle Park neighborhood. But if we look at each commercial property type, we find that for office space, the best location is the Research Triangle Park area.

Meanwhile, retail space opportunities are most abundant in the Old North Durham submarket. Alternatively, if you are looking for warehouse or other industrial space, consider looking at listings in Research Triangle Park.

Select your preferred property type from the search filters menu at the top of the search page and then navigate the interactive map for a better view of commercial real estate availability in the locations most suited to your needs.

Regardless of whether buying or leasing commercial space is a new experience for you, there are significant benefits to working with a commercial real estate broker. In addition to saving you time and money, an experienced broker will contribute specialist knowledge of the local market, the property type you need representation for, and will handle negotiations on your behalf in your best interest.

To start, it is important for you to have a good understanding of what kind of broker you need. For instance, there are differences between a tenant broker and a listing broker. Also important at the start is to have a clear idea of what kind of space (or tenant) you are looking for and what (if any) particular needs and requirements you might have. And, while it is good to get a referral, you should interview several brokers to better gauge who you feel would best represent your interests.

CommercialCafe hosts listings from some of the most trusted commercial real estate brokerages in the country. Use the contact form available on each listing page or the contact details for the property representatives to reach out and start your search!

The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself — which itself includes aspects such as location, property class, amenities, and the quality of the property management — to the local market conditions, the state of the local economy, the demand for that particular type of commercial property, and of course the costs of owning and maintaining it relative to what leasing rate or sale price you get from the property. Asking rents in the city went as high as $33.5 per square foot. In particular, the property type commanding the highest lease rates in Durham was Office space.

Conversely, the highest sale price last year was $73,500,000 that is located at 300 North Duke Street.

The average size of a commercial property in Durham depends greatly on the property type and the location — geographical possibilities and zoning allowances have significant influence on how big developers can build. While there are outliers that break height or volume records in the city, we can look at some average sizes by property use:

In Durham, the average size of an office property is 101,132 square feet.
Retail properties here incorporate an average of 67,537 square feet.
Industrial space in Durham is in buildings that are, on average 81,358 square feet in size.

Durham, NC Currently Available Listings

Commercial Space for Lease Breakdown

Commercial real estate listings for rent in Durham currently add up to 7,943,199 square feet. The market offers 127 active office listing(s), which amount to 5,023,430 square feet and account for 64% of commercial spaces on the market. Local retail availability includes 321,469 square feet across 43 retail space(s). Industrial space for rent opportunities in Durham amount to 1,699,865 square feet across a total of 19 warehouse and other industrial listing(s).

Property Type	Count of Listings	Total SF
Office	127	5,023,430
Retail	43	321,469
Industrial	19	1,699,865
Other	9	898,435

Commercial Space for Sale Breakdown

What’s more, if you are interested in making an investment in the local market, you can also find commercial real estate for sale in Durham, NC. Currently, there is 288,095 square feet of commercial property for sale here , which includes 11 office building(s) for sale , 4 retail investment opportunity listing(s) , and 2 listing(s) of industrial real estate property for sale .

Property Type	Count of Listings	Total SF
Office	11	127,105
Retail	4	28,856
Industrial	2	87,756
Other	33	44,378

Durham, NC Commercial Real Estate Market Overview

The City of Durham is strategically located in the heart of North Carolina, thanks to Bartlett S. Durham — the man who donated his land for a railroad station, which laid the city’s initial foundation. At first, Durham thrived as a hub for the tobacco industry. Today, the city is a confluence of education, creativity, industry and innovation. Commercial real estate in Durham serves a diverse economy in which technology, healthcare and education are the main industries.

Along with Raleigh and Chapel Hill, Durham makes up what is commonly referred to as The Triangle — Raleigh-Durham-Chapel Hill Research Triangle Park or RTP for short — a high-tech research and development center that has greatly revitalized the region following deindustrialization. In addition to research and development, local commercial inventory caters to manufacturing activity; logistical and storage enterprise; and business services firms. Moreover, the several notable institutions of higher education located in the city produce a steady outflow of highly skilled talent, giving Durham one of the most concentrated STEM labor pools in the country.

Durham, NC Commercial Real Estate for Lease and Sale

Frequently Asked Questions

What are the different types of commercial real estate?

What types of commercial real estate are available in Durham, NC?

What factors affect the price of commercial real estate in Durham, NC?

What is the average rent for commercial space in Durham, NC?

What are the best areas for commercial real estate in Durham, NC?

How do I find a good commercial real estate broker?

What is the most profitable commercial real estate?

What is the average size of a commercial property in Durham, NC?

Durham, NC Currently Available Listings

Commercial Space for Lease Breakdown

Commercial Space for Sale Breakdown

Durham, NC Commercial Real Estate Market Overview

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