Innovation Square

2220 E 105th St, Cleveland, OH 44010

  • For Lease Contact for pricing
  • Property Type VacantLand
  • Lot Size 0.7 Acre
  • Date Updated Apr 21, 2025
This highly visible development site lies within Cleveland’s transformative Opportunity Corridor, connecting I-490 to University Circle through the heart of the Fairfax neighborhood. The site—just steps from the Cleveland Clinic Main Campus—is surrounded by public and private investments reshaping the area into a hub for innovation, healthcare, and mixed-use development. Nearby residential projects like Axis at Ansel (163 units) and Innova (177 units) support a growing, walkable community. Additionally, the property is within walking distance to the new Fairfax Meijer, a full-service grocery and neighborhood anchor.
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Highlights

  • .70 AC available for ground lease or sale within the Opportunity Corridor
  • Potential to expand assemblage
  • Prime land assemblage with visibility and access
  • Adjacent to Cleveland Clinic Main Campus and walking distance to Fairfax Meijer, Medley Apartments, and Saucy Brew Works
  • Surrounded by over 700+ apartment unites within a 1/2 mile radius, including Medley, Axis at Ansel, Aura at Innovation Square, and Skyline on Stokes
  • Less than 1 mile from Case Western Reserve University and University Circle

Spaces Available

Contacts

broker

Passov Real Estate Group

Location

Getting Around

  • Walk Score ®

    55/100 Somewhat Walkable
  • Transit Score ®

    59/100 Good Transit
  • Bike Score ®

    45/100 Somewhat Bikeable
Powered by Walk Score ®
  • City Cleveland, OH
  • Neighborhood Fairfax
  • Zip Code 44010
  • Market Cleveland Akron

Points of Interest

  • Buckeye–Woodhill

    1.04 miles

  • East 79th

    1.49 miles

  • Coventry

    1.89 miles

  • Superior

    2.16 miles

  • East 55th

    2.23 miles

  • Stokes-Windermere Station

    2.78 miles

  • South Harbor

    3.85 miles

  • East 9th–North Coast

    4.11 miles

  • Cleveland Amtrak

    4.22 miles

  • Settlers Landing

    4.40 miles

  • Prestige Petrol

    0.89 miles

  • Sunoco

    0.94 miles

  • Fuel Point

    1.10 miles

  • Get Go

    1.15 miles

  • Gas USA

    1.36 miles

  • BP

    1.48 miles

  • Valero

    1.76 miles

  • Shell

    1.78 miles

  • Ohio Gas

    1.83 miles

  • South-East Harley Davidson

    7.53 miles

  • Cleveland Clinic Parking (P2) - Skyway access on level 3

    0.24 miles

  • W. O. Walker Center Garage

    0.35 miles

  • VISITOR LOT Lot S-63

    0.60 miles

  • Cleveland Clinic Parking (P1) - Elevators On SE Corner - Pedestrian Tunnel On Basement (B) Level

    0.61 miles

  • Underground and Surface Parking

    0.61 miles

  • Guest Parking 10 min.

    0.61 miles

  • Lot 13

    0.64 miles

  • Veale Center Parking Garage

    0.64 miles

  • SP+ Lot 82

    0.67 miles

  • UH Parking Garage

    0.67 miles

  • Tudor Arms Hotel

    0.26 miles

  • InterContinental Hotel Cleveland

    0.34 miles

  • Residence Inn

    0.60 miles

  • InterContinental Suites Hotel Cleveland

    0.62 miles

  • Holiday Inn Cleveland Clinic

    0.68 miles

  • Courtyard Cleveland University Circle

    0.90 miles

  • Glidden House

    1.02 miles

  • The Lancer

    1.05 miles

  • Tru by Hilton

    1.44 miles

  • Star's Compound

    2.30 miles

  • Tudor Bar & Grill

    0.26 miles

  • Domino's

    0.59 miles

  • Penn Station

    0.60 miles

  • Phuel Cafe

    0.60 miles

  • Fluffy Duck Cafe

    0.60 miles

  • Urban Kitchen

    0.61 miles

  • Table 45

    0.63 miles

  • Einstein Bros. Bagels

    0.73 miles

  • Atrium Café

    0.74 miles

  • Burger King

    0.76 miles

  • Bolton Elementary School

    0.24 miles

  • John Hay High School

    0.36 miles

  • Cleveland School of the Arts

    0.44 miles

  • CWRU Health Education Campus (HEC)

    0.58 miles

  • (future development, path)

    0.65 miles

  • Research Campus, CWRU School of Medicine

    0.73 miles

  • Saint Adalbert School

    0.73 miles

  • Charles Orr Academy

    0.80 miles

  • Case Western Reserve University

    0.86 miles

  • Sunbeam Elementary School

    0.95 miles

  • Kindercare Daycare

    0.61 miles

  • Character Academy Early Learning Center

    1.05 miles

  • Head Start Pre-School

    1.73 miles

  • Learning To Grow

    1.98 miles

  • Katai's Child Care Center

    2.15 miles

  • Oakfield Child Care Center

    2.52 miles

  • Laveer Child Care

    2.82 miles

  • EBC Child Care

    3.15 miles

  • Brightside Academy

    3.15 miles

  • The Centers for Families and Children

    3.19 miles

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broker

Passov Real Estate Group

  1. 1Main information
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