San Diego, CA Commercial Real Estate for Lease and Sale

Explore 1,106 listings of San Diego commercial real estate to find the best space for your business.

Moda Sorrento

5550 Oberlin Dr, Sorrento Valley, San Diego, CA
Property

Office

22,399 SF
Availability

2 Spaces

22,940 SF
Year Built

1984
For Lease Contact for pricing
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12411 Rancho Bernardo

12411 Rancho Bernardo, Rancho Bernardo, San Diego, CA
Property

Retail

1,640 SF
Availability

1 Space

1,640 SF
For Lease Contact for pricing
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The Spreckels Building

900 7th Ave, Core - Columbia, San Diego, CA
Property

Retail

108,000 SF
Availability

4 Spaces

20,898 SF
For Lease Contact for pricing
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3674 7th Ave

3674 7th Ave, Hillcrest, San Diego, CA
Property

Special

6,345 SF
Availability

1 Space

5,367 SF
For Lease Contact for pricing
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Office Coworking Retail Industrial

Office Retail Industrial Land
6342 Ferris Sq

6342 Ferris Sq, Sorrento Valley, San Diego, CA
Property

Office

5,788 SF
Availability

2 Spaces

5,788 SF
Year Built

1987
For Lease Contact for pricing
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Black Mountain Plaza

9323-9393 Activity Rd., Miramar, San Diego, CA
Property

Industrial

70,090 SF
Availability

3 Spaces

3,600 SF
Year Built

1979
For Lease

$19.80 - $21.00/SF/YR
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Fully Fixturized Restaurant with Patio

12955 El Camino Real, Carmel Valley, San Diego, CA
Property

Retail

10,350 SF
Year Built

1993
For Sale

$600,000
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2699 Commercial Street

2699 Commercial Street, Logan Heights, San Diego, CA
Property

Unassigned
For Sale Contact for pricing
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6980 Calle DE Linea

6980 Calle DE Linea, Otay Mesa, San Diego, CA
Property

Industrial

4,450 SF
Availability

1 Space

4,450 SF
Year Built

1993
For Lease Contact for pricing
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2642 - 2648 44th Street

2642 - 2648 44th Street, Swan Canyon, San Diego, CA
Property

Multi-Family

6,185 SF
For Sale

$2,400,000
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Landmark at Otay - Building 4

1910 Landmark Road, Otay Mesa, San Diego, CA
Property

Industrial

235,085 SF
Availability

1 Space

235,085 SF
Year Built

2023
For Lease Contact for pricing
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Fairmount Business Park

10981 San Diego Mission Rd, Grantville, San Diego, CA
Property

Office

21,170 SF
Availability

3 Spaces

5,532 SF
For Lease

$1.90 - $2.05/SF/MO
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5050 Milton St

5050 Milton St, Bay Park, San Diego, CA
Property

Special

10,000 SF
Availability

1 Space

7,450 SF
Year Built

1900
For Lease Contact for pricing
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6134 Nancy Ridge Dr.

6134 Nancy Ridge Dr., Sorrento Valley, San Diego, CA
Property

Unassigned

25,861 SF
Availability

1 Space

25,861 SF
Year Built

1987
For Lease Contact for pricing
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3861 Front St

3861 Front St, Hillcrest, San Diego, CA
Property

Office

3,361 SF
Year Built

1953
For Sale

$2,950,000
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2141-2155 Newton Avenue

2141 Newton Ave, Barrio Logan, San Diego, CA
Property

Industrial

19,700 SF
For Sale

$3,900,000
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15807-15883 Bernardo Center Dr

15807-15883 Bernardo Center Dr, Rancho Bernardo, San Diego, CA
Property

Retail

20,590 SF
Availability

1 Space

900 SF
For Lease Contact for pricing
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Otay Border Crossings - Building 2

7811 Paseo De La Fuente, Otay Mesa, San Diego, CA
Property

Industrial

46,177 SF
Availability

2 Spaces

46,177 SF
Year Built

2024
For Lease Contact for pricing
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Otay Business Park - Bldg. 1

1 Via De La Amistad, Otay Mesa, San Diego, CA
Property

Industrial

203,200 SF
Availability

1 Space

203,200 SF
Year Built

2025
For Lease Contact for pricing
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LEASING PROMO: First 6 Months - $0.85/SF NNN* *Predicated on a 3 year term signed by October 1, 2024 - ±44,000 SF Industrial Building on a ±2.84 Acre Lot

7565-7595 Carroll Rd, Miramar, San Diego, CA
Property

Other
Availability

1 Space

44,000 SF
For Lease Contact for pricing
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Otay Business Park - Bldg. 4

4 Via De La Amistad, Otay Mesa, San Diego, CA
Property

Industrial

190,320 SF
Availability

1 Space

190,320 SF
Year Built

2025
For Lease Contact for pricing
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7740 Formula Pl

7740 Formula Pl, Miramar, San Diego, CA
Property

Industrial

9,300 SF
Availability

1 Space

9,300 SF
Year Built

1981
For Lease

$1.80/SF/YR
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1350 6th Ave

1350 6th Ave, Core - Columbia, San Diego, CA
Property

Retail

5,769 SF
Availability

2 Spaces

3,206 SF
Year Built

1991
For Lease Contact for pricing
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2240 5th Avenue

2240 5TH AVE, Bankers Hill - Park West, San Diego, CA
Property

Office

4,337 SF
For Sale

$2,925,000
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OBX Otay Border Crossings - Building 4

7820 Paseo De La Fuente, Otay Mesa, San Diego, CA
Property

Industrial

205,832 SF
For Sale Contact for pricing
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Plaza Rancho Penasquitos

9821-10025 Carmel Mountain Rd., Rancho Penasquitos, San Diego, CA
Property

Retail

167,705 SF
Availability

2 Spaces

5,600 SF
Year Built

1980
For Lease Contact for pricing
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San Diego Distribution Center

7603 Saint Andrews Avenue, Otay Mesa, San Diego, CA
Property

Industrial

16,000 SF
Availability

1 Space

16,000 SF
For Lease

$1.25/SF/YR
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2607 1st Ave

2607 1st Ave, Bankers Hill - Park West, San Diego, CA
Property

Other
Year Built

2018
For Sale

$3
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3676 Main Street

3676 Main Street, Barrio Logan, San Diego, CA
Property

Industrial

2,560 SF
For Sale Contact for pricing
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1666 Euclid Ave

1666 Euclid Ave, Ridgeview - Webster, San Diego, CA
Property

VacantLand

29,620 SF
Availability

1 Space

29,620 SF
Year Built

1965
For Lease Contact for pricing
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1346 S. 28th St.

1346 S. 28th St., Barrio Logan, San Diego, CA
Property

Industrial

25,232 SF
Availability

1 Space

25,232 SF
Year Built

1955
For Lease

$18.00/SF/YR
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One Alexandria Square South - Bldg. 3

10935 N. Torrey Pines Rd., University City, San Diego, CA
Property

Unassigned

119,202 SF
Availability

1 Space

82,514 SF
Year Built

2024
For Lease Contact for pricing
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Gaslamp City Square

425-455 Island Ave San Diego, Gaslamp, San Diego, CA
Property

Retail

57,000 SF
Availability

3 Spaces

15,171 SF
For Lease Contact for pricing
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Bond Ranch Business Park

10140 Marconi Dr, Otay Mesa, San Diego, CA
Property

Industrial

16,104 SF
Availability

1 Space

2,087 SF
Year Built

1992
For Lease

$1.45/SF/MO
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7270 Trade St

7270 Trade St, Miramar, San Diego, CA
Property

Office

20,152 SF
Availability

2 Spaces

9,820 SF
Year Built

2004
For Lease Contact for pricing
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Palm Plaza

3350 Palm Ave, Otay Mesa West, San Diego, CA
Property

Retail

23,200 SF
Availability

1 Space

1,465 SF
Year Built

1971
For Lease Contact for pricing
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INDUSTRIAL SPACE FOR SUBLEASE

6191 Cornerstone Court, Sorrento Valley, San Diego, CA
Property

Industrial
Availability

1 Space

1,881 SF
For Lease Contact for pricing
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201 Fir St

201 Fir St, Bankers Hill - Park West, San Diego, CA
Property

Special

10,900 SF
For Sale Contact for pricing
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541 4th Avenue

541 4th Avenue, Gaslamp, San Diego, CA
Property

Retail

1,200 SF
Availability

1 Space

1,200 SF
For Lease

$4.00/SF/MO
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Building K

6030 Village Way, Carmel Valley, San Diego, CA
Property

Office

7,619 SF
Availability

1 Space

7,619 SF
For Lease Contact for pricing
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5302 Napa St

5302 Napa St, Morena, San Diego, CA
Property

Retail

9,203 SF
Availability

1 Space

9,203 SF
Year Built

2000
For Lease Contact for pricing
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Medical Park with Waterfront Location

Liberty Station - 2790 Truxtun Road San Diego, Midway, San Diego, CA
Property

Office
Availability

1 Space

3,802 SF
For Lease Contact for pricing
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FULLY LEASED | Office Space For Lease | Equus Plaza in Mission Valley

2635 Camino del Rio S, Mission Valley East, San Diego, CA
Property

Other
Availability

1 Space

42,160 SF
Year Built

1984
For Lease Contact for pricing
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Del Rio Plaza

3703 Camino Del Rio S, Mission Valley East, San Diego, CA
Property

Office

22,595 SF
Availability

2 Spaces

11,049 SF
Year Built

1989
For Lease

$2.00 - $3.50/SF/MO
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Landmark at Otay - Building 5 & 6

8425 Otay Mesa Road, Otay Mesa, San Diego, CA
Property

Industrial

256,789 SF
Availability

6 Spaces

256,796 SF
Year Built

2024
For Lease Contact for pricing
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±10,284 Square Foot Building Dock-High & Grade-Level Loading

7010 Carroll Rd, Sorrento Valley, San Diego, CA
Property

Industrial
Availability

1 Space

10,284 SF
For Lease Contact for pricing
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1370 India Street

1370 India St, Core - Columbia, San Diego, CA
Property

Office

22,155 SF
Availability

1 Space

9,685 SF
Year Built

1988
For Lease Contact for pricing
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13th & J

403 13th St, East Village, San Diego, CA
Property

Retail

5,000 SF
Availability

1 Space

5,000 SF
For Lease

$2.50 - $4.00/SF/MO
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Blvd63

6345 El Cajon Blvd, Rolando, San Diego, CA
Property

Retail

416,171 SF
Availability

4 Spaces

4,851 SF
Year Built

2014
For Lease Contact for pricing
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1747 Pacific Highway

1747 Pacific Highway, Harborview, San Diego, CA
Property

Unassigned
For Sale Contact for pricing
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1430 National Avenue

1430 National Avenue, Barrio Logan, San Diego, CA
Property

Industrial

20,197 SF
Availability

1 Space

19,900 SF
For Lease Contact for pricing
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8780 Navajo Road

8780 Navajo Road, Lake Murray, San Diego, CA
Property

Retail

33,958 SF
Availability

1 Space

33,958 SF
For Lease Contact for pricing
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Frequently Asked Questions

Commercial real estate is a broad category that includes a high variety of space types designed to meet the needs of various industries of the local economy and their specialized subsectors, as presented in our real estate 101 guide to types of commercial real estate. However, there are three main categories that you are most likely to come across: office, retail, and industrial space.

Modern office space is typically organized over large floor plates bound by high ceilings and large windows for an abundance of natural light and is located in transit-oriented developments with good access to multiple modes of transportation, so as to facilitate employee commute. The San Diego commercial real estate market incorporates 44,845,196 square feet of office space across 506 buildings.

Office buildings can also accommodate coworking spaces, which are shared office options that typically cater to the needs of small, startup businesses that require flexible workspaces, a concentration of amenities, and services that can be accessed on an occasional or short-term basis. In San Diego, the coworking segment of the commercial real estate market incorporates about 1,615 square feet.
Retail space includes shopping malls, department stores, street retail, or specialty stores dedicated to a narrow range of products. Such properties are typically located in high foot-traffic and/or car traffic areas, to facilitate customer access. The San Diego commercial real estate market includes 11,739,710 square feet of retail space in a variety of settings.
Industrial property most often serves businesses operating in manufacturing or logistics and generally consists of large open spaces located within good access to roads, railways, freight airports or regional water ports. Industrial space listings can include warehouses, manufacturing plants, distribution centers, flexible industrial space, or even data center facilities. Across the San Diego market, there is a total of 19,916,079 square feet of industrial property.

The listing inventory in San Diego incorporates commercial real estate for lease and for sale of almost all property types and subtypes. However, you’ll find some categories offer more rental or investment opportunities than others.

The largest share of commercial real estate space for lease in San Diego is represented by Office space, which accounts for 15,406,350 square feet of available listings. Industrial space available in San Diego adds up to 9,258,282 square feet.

Meanwhile, most of the listings of commercial property for sale in San Diego are in the Industrial category.

The price of renting or buying commercial real estate is influenced by a variety of factors, including: the property type (for example, office space is priced higher than other property types in most locations); the condition and asset class rating (property rated class A or above will typically command a higher price than lower grade classifications); the quality or the development potential of the property location; whether or not there is high demand for the type of commercial asset in question; and what the state of supply is relative to demand.

The average rent for commercial real estate space listed for lease in San Diego is $31.13 per square foot. However, this value does not offer enough perspective on its own, as you will find significant variation in prices across property types, property classes, and location, as well as other impacting factors. For instance, rent per square foot of office space in San Diego can vary greatly depending on the rating of the property from Class A to Class C, as well as across the city depending on the location of the asset. What’s more, each commercial property type makes its own rent market: while the average rent for office space rested at $41.6 per square foot, industrial space in San Diego saw average rents of $19.9 per square foot.

Whether you are looking for commercial real estate for lease or commercial property for sale, the best choice of location depends on the factors that are most relevant to your business strategy. A good thing to look for at the start, however, is the areas of the city that have the highest concentration of your preferred type of property, as these areas are generally well connected to the amenities and points of interest that are most relevant to each property type.

As such, there are several areas that you could consider to be the best location for commercial real estate in San Diego, depending on the property type you are interested in. The highest concentration of commercial space listings of any kind in San Diego is in the Core - Columbia neighborhood. But if we look at each commercial property type, we find that for office space, the best location is the Core - Columbia area.

Meanwhile, retail space opportunities are most abundant in the Midway submarket. Alternatively, if you are looking for warehouse or other industrial space, consider looking at listings in Otay Mesa.

Select your preferred property type from the search filters menu at the top of the search page and then navigate the interactive map for a better view of commercial real estate availability in the locations most suited to your needs.

Regardless of whether buying or leasing commercial space is a new experience for you, there are significant benefits to working with a commercial real estate broker. In addition to saving you time and money, an experienced broker will contribute specialist knowledge of the local market, the property type you need representation for, and will handle negotiations on your behalf in your best interest.

To start, it is important for you to have a good understanding of what kind of broker you need. For instance, there are differences between a tenant broker and a listing broker. Also important at the start is to have a clear idea of what kind of space (or tenant) you are looking for and what (if any) particular needs and requirements you might have. And, while it is good to get a referral, you should interview several brokers to better gauge who you feel would best represent your interests.

CommercialCafe hosts listings from some of the most trusted commercial real estate brokerages in the country. Use the contact form available on each listing page or the contact details for the property representatives to reach out and start your search!

The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself — which itself includes aspects such as location, property class, amenities, and the quality of the property management — to the local market conditions, the state of the local economy, the demand for that particular type of commercial property, and of course the costs of owning and maintaining it relative to what leasing rate or sale price you get from the property. Asking rents in the city went as high as $192 per square foot. In particular, the property type commanding the highest lease rates in San Diego was Office space.

Conversely, the highest sale price last year was $148,250,000 that is located at 9233 Balboa Avenue.

The average size of a commercial property in San Diego depends greatly on the property type and the location — geographical possibilities and zoning allowances have significant influence on how big developers can build. While there are outliers that break height or volume records in the city, we can look at some average sizes by property use:

In San Diego, the average size of an office property is 99,656 square feet.
Retail properties here incorporate an average of 65,585 square feet.
Industrial space in San Diego is in buildings that are, on average 83,331 square feet in size.

San Diego, CA Currently Available Listings

Commercial Space for Lease Breakdown

Commercial real estate listings for rent in San Diego currently add up to 29,579,270 square feet. The market offers 468 active office listing(s), which amount to 15,589,372 square feet and account for 52% of commercial spaces on the market. Local retail availability includes 1,700,938 square feet across 166 retail space(s). Industrial space for rent opportunities in San Diego amount to 9,221,588 square feet across a total of 233 warehouse and other industrial listing(s).

Property Type	Count of Listings	Total SF
Office	468	15,589,372
Retail	166	1,700,938
Industrial	233	9,221,588
Other	28	3,067,372

Commercial Space for Sale Breakdown

What’s more, if you are interested in making an investment in the local market, you can also find commercial real estate for sale in San Diego, CA. Currently, there is 2,342,569 square feet of commercial property for sale here , which includes 31 office building(s) for sale , 24 retail investment opportunity listing(s) , and 36 listing(s) of industrial real estate property for sale .

Property Type	Count of Listings	Total SF
Office	31	322,693
Retail	24	196,623
Industrial	36	1,439,759
Other	64	383,494

San Diego, CA Commercial Real Estate Market Overview

Located just 120 miles south of Los Angeles on the coast of the Pacific Ocean, San Diego, Calif., is well-known for its sunny beaches and long-standing U.S. Navy presence. The city’s proximity to the Mexican border also makes it an international business hub, as well as a culturally diverse community.

San Diego’s economy revolves around a variety of industries — including military and defense, international trade, tourism, research and manufacturing, and biotechnology — which sustain a thriving commercial real estate market. What’s more, companies that decide to make San Diego their home have easy access to talent from the University of California San Diego, San Diego State University, and many other universities and colleges in the area.

San Diego, CA Commercial Real Estate for Lease and Sale

Frequently Asked Questions

What are the different types of commercial real estate?

What types of commercial real estate are available in San Diego, CA?

What factors affect the price of commercial real estate in San Diego, CA?

What is the average rent for commercial space in San Diego, CA?

What are the best areas for commercial real estate in San Diego, CA?

How do I find a good commercial real estate broker?

What is the most profitable commercial real estate?

What is the average size of a commercial property in San Diego, CA?

San Diego, CA Currently Available Listings

Commercial Space for Lease Breakdown

Commercial Space for Sale Breakdown

San Diego, CA Commercial Real Estate Market Overview

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