San Diego, CA Commercial Real Estate for Lease and Sale

Explore 1,106 listings of San Diego commercial real estate to find the best space for your business.

4455 Morena Blvd

4455 Morena Blvd #104, Bay Ho, San Diego, CA
Property

Office

1,555 SF
Year Built

1980
For Sale Contact for pricing
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Mission Valley Sublease | 2,844 RSF | Sublease: Expires 6/30/2028

5333 Mission Center Rd, Mission Valley East, San Diego, CA
Property

Office
Availability

1 Space

2,844 SF
For Lease Contact for pricing
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1277-1287 Morena Blvd.

1277-1287 Morena Blvd., Morena, San Diego, CA
Property

Retail

8,748 SF
Availability

1 Space

3,500 SF
For Lease Contact for pricing
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3956-3962 1st Ave

3956-3962 1st Ave, Hillcrest, San Diego, CA
Property

Multi-Family

10,400 SF
Year Built

1955
For Sale

$7,000,000
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Office Coworking Retail Industrial

Office Retail Industrial Land
Old Town Professional Building

2356 Moore St, Old Town San Diego, San Diego, CA
Property

Office

12,046 SF
Availability

2 Spaces

2,323 SF
Year Built

1977
For Lease

$2.25/SF/MO
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2608 Imperial Ave

2608 Imperial Ave, Grant Hill, San Diego, CA
Property

Retail

5,000 SF
For Sale Contact for pricing
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Pacific Rim Trade Center

1605 Pacific Rim Ct., Otay Mesa, San Diego, CA
Property

Industrial

13,594 SF
Availability

1 Space

13,594 SF
Year Built

1991
For Lease Contact for pricing
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23,734 SF Industrial Warehouse Building For Lease

2155 Britannia Blvd, Otay Mesa, San Diego, CA
Property

Industrial
Availability

1 Space

23,734 SF
For Lease Contact for pricing
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7585 Mission Gorge Rd

7585 Mission Gorge Rd, Allied Gardens, San Diego, CA
Property

Retail

3,019 SF
Availability

1 Space

3,019 SF
For Lease

$3.05/SF/MO
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1980 Kettner Blvd

1980 Kettner Blvd, Harborview, San Diego, CA
Property

Retail

163,722 SF
Availability

2 Spaces

1,744 SF
Year Built

2014
For Lease Contact for pricing
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Mt. Soledad Business Park

2621-2637 Ariane Dr., Bay Ho, San Diego, CA
Property

Industrial

13,553 SF
Availability

1 Space

1,470 SF
Year Built

1979
For Lease Contact for pricing
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Otay Business Park - Bldg. 1

1 Via De La Amistad, Otay Mesa, San Diego, CA
Property

Industrial

203,200 SF
Availability

1 Space

203,200 SF
Year Built

2025
For Lease Contact for pricing
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SWC Siempre Viva Road & Cactus Road

SWC Siempre Viva Road & Cactus Road, Otay Mesa, San Diego, CA
Property

VacantLand

0.91 Acre
For Sale Contact for pricing
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1013 Morena Blvd.

1013 Morena Blvd., Morena, San Diego, CA
Property

Unassigned
Year Built

1954
For Sale Contact for pricing
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The Campus at Horton - Bldg. 100

100 Horton Plz., Horton Plaza, San Diego, CA
Property

Unassigned

377,977 SF
Availability

9 Spaces

377,977 SF
Year Built

2024
For Lease Contact for pricing
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Bernardo Gateway

10875 Rancho Bernardo Rd, Rancho Bernardo, San Diego, CA
Property

Office
Availability

1 Space

13,739 SF
For Lease Contact for pricing
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4451-65 University Ave

4451-65 University Ave, Chollas Creek, San Diego, CA
Property

Retail

7,080 SF
Availability

1 Space

1,200 SF
For Lease Contact for pricing
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4455 Morena Blvd

4455 Morena Blvd #116, Bay Ho, San Diego, CA
Property

Office

732 SF
Year Built

1980
For Sale

$375,000
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+- 1,679 SF Office Condominium - For Sale

9888 Carroll Centre Road, Suite 225, Mira Mesa, CA, CA
Property

Office

52,421 SF
Year Built

1985
For Sale Contact Agent For Pricing
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INDUSTRIAL SPACE FOR SUBLEASE

6191 Cornerstone Court, Sorrento Valley, San Diego, CA
Property

Industrial
Availability

1 Space

1,881 SF
For Lease Contact for pricing
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4603 Mission Blvd

4603 Mission Blvd, Pacific Beach, San Diego, CA
Property

Retail

8,005 SF
Availability

2 Spaces

1,499 SF
Year Built

1985
For Lease Contact for pricing
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4888 Cass St

4888 Cass St, Pacific Beach, San Diego, CA
Property

Retail

1,846 SF
Availability

1 Space

1,846 SF
For Lease Contact for pricing
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Bernardo Center

16495 Bernardo Center Dr, Rancho Bernardo, San Diego, CA
Property

Retail

6,540 SF
Availability

1 Space

6,540 SF
Year Built

1986
For Lease Contact for pricing
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Otay Business Park - Bldg. 9

9 Via De La Amistad, Otay Mesa, San Diego, CA
Property

Industrial

196,960 SF
Availability

1 Space

196,960 SF
Year Built

2035
For Lease Contact for pricing
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CLASS A INDUSTRIAL BUILDING FOR SALE OR LEASE | 150,530 SF

7129 Enrico Fermi Pl, Otay Mesa, San Diego, CA
Property

Industrial

41,500 SF
For Sale Contact for pricing
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Runway Distribution Center Bldg 2

9050 Airway Rd San Diego, Otay Mesa, San Diego, CA
Property

Industrial

59,905 SF
Availability

1 Space

59,905 SF
For Lease Contact for pricing
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9373 Hazard Way

9373 Hazard Way, Kearny Mesa, San Diego, CA
Property

Office
Availability

1 Space

10,655 SF
For Lease Contact for pricing
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30th & University

2926 University Avenue, North Park, San Diego, CA
Property

Retail

4,000 SF
Availability

1 Space

4,000 SF
For Lease Contact for pricing
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Otay Border Crossings - Building 2

7811 Paseo De La Fuente, Otay Mesa, San Diego, CA
Property

Industrial

46,177 SF
Availability

2 Spaces

46,177 SF
Year Built

2024
For Lease Contact for pricing
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6760 Top Gun St

6760 Top Gun St, Sorrento Valley, San Diego, CA
Property

Office

24,750 SF
Availability

1 Space

12,140 SF
Year Built

1999
For Lease

$2.25/SF/MO
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Dollar Tree | New Store Locations | Under Renovation

1862 Palm Ave, Egger Highlands, San Diego, CA
Property

Retail

14,577 SF
For Sale

$5,215,000
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Britannia Tech Park

7498 Colchester Ct., Otay Mesa, San Diego, CA
Property

Industrial

102,099 SF
Availability

1 Space

50,000 SF
Year Built

2023
For Lease Contact for pricing
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Western Otay Mesa Industrial Development Opportunity - Three (3) Industrial Lots for Sale 2 AC, 2.34 AC, & 5.58 AC (9.92 Acres Total)

Exposition Way & Vista Santo Domingo, Ocean View Hills, San Diego, CA
Property

Other
For Sale Contact for pricing
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Otay Business Park - Bldg. 4

4 Via De La Amistad, Otay Mesa, San Diego, CA
Property

Industrial

190,320 SF
Availability

1 Space

190,320 SF
Year Built

2025
For Lease Contact for pricing
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Miramar Point Business Pk

7758 Arjons Dr, Miramar, San Diego, CA
Property

Industrial

4,994 SF
Year Built

1989
For Sale

$2,025,000
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Fourth & Juniper Executive Complex

2250 4th Ave, Bankers Hill - Park West, San Diego, CA
Property

Office

29,189 SF
For Sale

$7,500,000
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The Preserve at Torrey Highlands - Bldg. 2

Camino Del Sur, Rancho Penasquitos, San Diego, CA
Property

Office

120,000 SF
Availability

1 Space

120,000 SF
Year Built

2035
For Lease Contact for pricing
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Clairemont Corner

4592 Clairemont Dr, Bay Ho, San Diego, CA
Property

Retail

1,949 SF
Availability

1 Space

1,949 SF
Year Built

2009
For Lease Contact for pricing
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Rancho Bernardo Heights

15717 Bernardo Heights Pky, Rancho Bernardo, San Diego, CA
Property

Retail

5,314 SF
For Sale

$3,200,000
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8780 Navajo Road

8780 Navajo Road, Lake Murray, San Diego, CA
Property

Retail

33,958 SF
Availability

1 Space

33,958 SF
For Lease Contact for pricing
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SEC Alta Road

SEC Alta Road, Otay Mesa, San Diego, CA
Property

VacantLand

10 Acre
For Sale

$2,000,000
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3928-3930 El Cajon Blvd

3930 El Cajon Blvd, Normal Heights, San Diego, CA
Property

Retail

1,802 SF
Year Built

1952
For Sale

$1,400,000
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4109 Park Pl

4109 Park Pl, Kensington, San Diego, CA
Property

Multi-Family

4,735 SF
Year Built

1969
For Sale

$3,850,000
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San Diego Distribution Center

7603 Saint Andrews Avenue, Otay Mesa, San Diego, CA
Property

Industrial

16,000 SF
Availability

1 Space

16,000 SF
For Lease

$1.25/SF/YR
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Midway Industrial Park

2775-2785 Kurtz St, Midway, San Diego, CA
Property

Industrial

50,526 SF
Availability

1 Space

2,000 SF
Year Built

1974
For Lease

$2.20/SF/MO
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Banker's Hill Villas

2132 Brant Street, Bankers Hill - Park West, San Diego, CA
Property

Multi-Family

2,756 SF
Year Built

1938
For Sale

$1,700,000
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3175-3185 Midway Drive

3185 Midway Drive, Midway, San Diego, CA
Property

Retail

25,077 SF
Availability

3 Spaces

5,457 SF
Year Built

1988
For Lease

$2.25 - $2.45/SF/MO
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Gaslamp City Square

425-455 Island Ave San Diego, Gaslamp, San Diego, CA
Property

Retail

57,000 SF
Availability

3 Spaces

15,171 SF
For Lease Contact for pricing
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110 W. Ash St.

110 W. Ash St., Cortez, San Diego, CA
Property

Unassigned
Year Built

1900
For Sale Contact for pricing
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Park Summit

575 Upas St, Bankers Hill - Park West, San Diego, CA
Property

Retail

7,416 SF
Availability

4 Spaces

7,416 SF
For Lease Contact for pricing
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LEASING PROMO: First 6 Months - $0.85/SF NNN* *Predicated on a 3 year term signed by October 1, 2024 - ±44,000 SF Industrial Building on a ±2.84 Acre Lot

7565-7595 Carroll Rd, Miramar, San Diego, CA
Property

Other
Availability

1 Space

44,000 SF
For Lease Contact for pricing
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4S Ranch Village Center

16625 Dove Canyon Road, 4S Ranch, San Diego, CA
Property

Retail

52,793 SF
Availability

2 Spaces

2,427 SF
Year Built

2002
For Lease Contact for pricing
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Frequently Asked Questions

Commercial real estate is a broad category that includes a high variety of space types designed to meet the needs of various industries of the local economy and their specialized subsectors, as presented in our real estate 101 guide to types of commercial real estate. However, there are three main categories that you are most likely to come across: office, retail, and industrial space.

Modern office space is typically organized over large floor plates bound by high ceilings and large windows for an abundance of natural light and is located in transit-oriented developments with good access to multiple modes of transportation, so as to facilitate employee commute. The San Diego commercial real estate market incorporates 44,845,196 square feet of office space across 506 buildings.

Office buildings can also accommodate coworking spaces, which are shared office options that typically cater to the needs of small, startup businesses that require flexible workspaces, a concentration of amenities, and services that can be accessed on an occasional or short-term basis. In San Diego, the coworking segment of the commercial real estate market incorporates about 1,615 square feet.
Retail space includes shopping malls, department stores, street retail, or specialty stores dedicated to a narrow range of products. Such properties are typically located in high foot-traffic and/or car traffic areas, to facilitate customer access. The San Diego commercial real estate market includes 11,739,710 square feet of retail space in a variety of settings.
Industrial property most often serves businesses operating in manufacturing or logistics and generally consists of large open spaces located within good access to roads, railways, freight airports or regional water ports. Industrial space listings can include warehouses, manufacturing plants, distribution centers, flexible industrial space, or even data center facilities. Across the San Diego market, there is a total of 19,916,079 square feet of industrial property.

The listing inventory in San Diego incorporates commercial real estate for lease and for sale of almost all property types and subtypes. However, you’ll find some categories offer more rental or investment opportunities than others.

The largest share of commercial real estate space for lease in San Diego is represented by Office space, which accounts for 15,406,350 square feet of available listings. Industrial space available in San Diego adds up to 9,258,282 square feet.

Meanwhile, most of the listings of commercial property for sale in San Diego are in the Industrial category.

The price of renting or buying commercial real estate is influenced by a variety of factors, including: the property type (for example, office space is priced higher than other property types in most locations); the condition and asset class rating (property rated class A or above will typically command a higher price than lower grade classifications); the quality or the development potential of the property location; whether or not there is high demand for the type of commercial asset in question; and what the state of supply is relative to demand.

The average rent for commercial real estate space listed for lease in San Diego is $31.13 per square foot. However, this value does not offer enough perspective on its own, as you will find significant variation in prices across property types, property classes, and location, as well as other impacting factors. For instance, rent per square foot of office space in San Diego can vary greatly depending on the rating of the property from Class A to Class C, as well as across the city depending on the location of the asset. What’s more, each commercial property type makes its own rent market: while the average rent for office space rested at $41.6 per square foot, industrial space in San Diego saw average rents of $19.9 per square foot.

Whether you are looking for commercial real estate for lease or commercial property for sale, the best choice of location depends on the factors that are most relevant to your business strategy. A good thing to look for at the start, however, is the areas of the city that have the highest concentration of your preferred type of property, as these areas are generally well connected to the amenities and points of interest that are most relevant to each property type.

As such, there are several areas that you could consider to be the best location for commercial real estate in San Diego, depending on the property type you are interested in. The highest concentration of commercial space listings of any kind in San Diego is in the Core - Columbia neighborhood. But if we look at each commercial property type, we find that for office space, the best location is the Core - Columbia area.

Meanwhile, retail space opportunities are most abundant in the Midway submarket. Alternatively, if you are looking for warehouse or other industrial space, consider looking at listings in Otay Mesa.

Select your preferred property type from the search filters menu at the top of the search page and then navigate the interactive map for a better view of commercial real estate availability in the locations most suited to your needs.

Regardless of whether buying or leasing commercial space is a new experience for you, there are significant benefits to working with a commercial real estate broker. In addition to saving you time and money, an experienced broker will contribute specialist knowledge of the local market, the property type you need representation for, and will handle negotiations on your behalf in your best interest.

To start, it is important for you to have a good understanding of what kind of broker you need. For instance, there are differences between a tenant broker and a listing broker. Also important at the start is to have a clear idea of what kind of space (or tenant) you are looking for and what (if any) particular needs and requirements you might have. And, while it is good to get a referral, you should interview several brokers to better gauge who you feel would best represent your interests.

CommercialCafe hosts listings from some of the most trusted commercial real estate brokerages in the country. Use the contact form available on each listing page or the contact details for the property representatives to reach out and start your search!

The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself — which itself includes aspects such as location, property class, amenities, and the quality of the property management — to the local market conditions, the state of the local economy, the demand for that particular type of commercial property, and of course the costs of owning and maintaining it relative to what leasing rate or sale price you get from the property. Asking rents in the city went as high as $192 per square foot. In particular, the property type commanding the highest lease rates in San Diego was Office space.

Conversely, the highest sale price last year was $148,250,000 that is located at 9233 Balboa Avenue.

The average size of a commercial property in San Diego depends greatly on the property type and the location — geographical possibilities and zoning allowances have significant influence on how big developers can build. While there are outliers that break height or volume records in the city, we can look at some average sizes by property use:

In San Diego, the average size of an office property is 99,656 square feet.
Retail properties here incorporate an average of 65,585 square feet.
Industrial space in San Diego is in buildings that are, on average 83,331 square feet in size.

San Diego, CA Currently Available Listings

Commercial Space for Lease Breakdown

Commercial real estate listings for rent in San Diego currently add up to 29,579,270 square feet. The market offers 468 active office listing(s), which amount to 15,589,372 square feet and account for 52% of commercial spaces on the market. Local retail availability includes 1,700,938 square feet across 166 retail space(s). Industrial space for rent opportunities in San Diego amount to 9,221,588 square feet across a total of 233 warehouse and other industrial listing(s).

Property Type	Count of Listings	Total SF
Office	468	15,589,372
Retail	166	1,700,938
Industrial	233	9,221,588
Other	28	3,067,372

Commercial Space for Sale Breakdown

What’s more, if you are interested in making an investment in the local market, you can also find commercial real estate for sale in San Diego, CA. Currently, there is 2,342,569 square feet of commercial property for sale here , which includes 31 office building(s) for sale , 24 retail investment opportunity listing(s) , and 36 listing(s) of industrial real estate property for sale .

Property Type	Count of Listings	Total SF
Office	31	322,693
Retail	24	196,623
Industrial	36	1,439,759
Other	64	383,494

San Diego, CA Commercial Real Estate Market Overview

Located just 120 miles south of Los Angeles on the coast of the Pacific Ocean, San Diego, Calif., is well-known for its sunny beaches and long-standing U.S. Navy presence. The city’s proximity to the Mexican border also makes it an international business hub, as well as a culturally diverse community.

San Diego’s economy revolves around a variety of industries — including military and defense, international trade, tourism, research and manufacturing, and biotechnology — which sustain a thriving commercial real estate market. What’s more, companies that decide to make San Diego their home have easy access to talent from the University of California San Diego, San Diego State University, and many other universities and colleges in the area.

San Diego, CA Commercial Real Estate for Lease and Sale

Frequently Asked Questions

What are the different types of commercial real estate?

What types of commercial real estate are available in San Diego, CA?

What factors affect the price of commercial real estate in San Diego, CA?

What is the average rent for commercial space in San Diego, CA?

What are the best areas for commercial real estate in San Diego, CA?

How do I find a good commercial real estate broker?

What is the most profitable commercial real estate?

What is the average size of a commercial property in San Diego, CA?

San Diego, CA Currently Available Listings

Commercial Space for Lease Breakdown

Commercial Space for Sale Breakdown

San Diego, CA Commercial Real Estate Market Overview

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