Cambridge, MA Commercial Real Estate for Lease and Sale

Explore 109 listings of Cambridge commercial real estate to find the best space for your business.

720 Massachusetts Avenue

720 Massachusetts Avenue, Riverside, Cambridge, MA
Property

Office

10,152 SF
Availability

1 Space

800 SF
For Lease Contact for pricing
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1950 Massachusetts Ave

1950 Massachusetts Ave , North Cambridge, Cambridge, MA
Property

Office

32,036 SF
Availability

2 Spaces

2,300 SF
For Lease Contact for pricing
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College House

1430 Massachusetts Avenue, West Cambridge, Cambridge, MA
Property

Office

50,000 SF
Availability

1 Space

8,265 SF
Year Built

1890
For Lease Contact for pricing
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School Campus Opportunity | Cambridge, Massachusetts

15 Notre Dame Avenue, North Cambridge, Cambridge, MA
Property

Other

54,148 SF
Availability

1 Space

54,148 SF
Year Built

1875
For Lease

$19.95/SF/YR
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Office Coworking Retail

Office Retail Industrial Land
Cambridge #0183
Staples Studio
186 Alewife Brook Parkway, Cambridge, MA
Services

Meeting Room

Dedicated Desk
Amenities

24/7 security

Bike storage

Complimentary coffee & tea

High-speed wifi

Parking

Printer

Privacy booths

Receptionist/Secretarial services

TV/Monitor

White boards
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Retail Opportunity

2500 Massachusetts Avenue, North Cambridge, Cambridge, MA
Property

Retail

2,500 SF
Availability Contact for availability

For Lease Contact for pricing
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CIC Cambridge - 1 Broadway (Kendall)
CIC
One Broadway, Cambridge, MA
Services

Open Workspace

Private Office

Dedicated Desk
Amenities

Bike storage

Complimentary coffee & tea

Game room

High-speed wifi

Kitchen

Mail services

Masseuse

Parking

Podcast room

Printer
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625 Massachusetts Avenue

625 Massachusetts Avenue, Area 4, Cambridge, MA
Property

Office

80,920 SF
Availability

2 Spaces

35,660 SF
Year Built

1950
For Lease Contact for pricing
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Parking lot at 483 Concord Ave in Cambridge

483 Concord Avenue, Peabody, Cambridge, MA
Property

VacantLand
For Sale

$850,000
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552 Massachusetts Ave

552 Massachusetts Ave, Cambridgeport, Cambridge, MA
Property

Office

34,617 SF
Availability

2 Spaces

2,900 SF
For Lease Contact for pricing
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150 Columbia St

150 Columbia St, Area 4, Cambridge, MA
Property

Retail

7,088 SF
Year Built

1890
For Sale

Subject To Offer
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Alexandria Center at Kendall Square - 225 Binney Street

225 Binney Street, East Cambridge, Cambridge, MA
Property

Office

305,212 SF
Availability

1 Space

114,000 SF
Year Built

2013
For Lease Contact for pricing
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28 WIllow Street

28 Willow St, Inman/ Harrington, Cambridge, MA
Property

Multi-Family

2,326 SF
Year Built

1902
For Sale

Subject To Offer
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The Charles Hotel

1 Bennett Street, West Cambridge, Cambridge, MA
Property

Retail

6,409 SF
Availability

1 Space

6,409 SF
For Lease Contact for pricing
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One Memorial

1 Memorial Drive, MIT, Cambridge, MA
Property

Office

409,422 SF
Availability

2 Spaces

300,000 SF
Year Built

1987
For Lease Contact for pricing
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60 First Street

60 First Street, East Cambridge, Cambridge, MA
Property

Retail

16,339 SF
Availability

1 Space

16,339 SF
For Lease Contact for pricing
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One Cambridge Place

50 Hampshire St, Area 4, Cambridge, MA
Property

Unassigned

202,023 SF
Availability

1 Space

29,520 SF
Year Built

1999
For Lease Contact for pricing
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186 Alewife Brook Parkway

186 Alewife Brook Parkway, Peabody, Cambridge, MA
Property

Office

224,001 SF
Availability

1 Space

3,700 SF
For Lease Contact for pricing
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185 Alewife Brook Pkwy

185 Alewife Brook Pkwy, Cambridge Highlands, Cambridge, MA
Property

Office

56,630 SF
Availability

1 Space

1,600 SF
For Lease Contact for pricing
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810 Memorial Drive at RIVERMARK

810 Memorial Drive, Cambridgeport, Cambridge, MA
Property

Office

28,218 SF
Availability

10 Spaces

11,880 SF
For Lease Contact for pricing
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Harvard Square
Regus
One Mifflin Place Suite 400, Cambridge, MA
Services

Virtual Office

Open Workspace

Private Office

Dedicated Desk
Amenities

24/7 security

Access to global network

Business address

Business lounge

Cleaning services

Ergonomic furniture

Lounge area

Mail services

Money-back guarantee

Office furniture
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44 Brattle Street

44 Brattle Street, West Cambridge, Cambridge, MA
Property

Office

68,946 SF
Availability

2 Spaces

8,877 SF
Year Built

1970
For Lease Contact for pricing
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201 Broadway

201 Broadway, Area 4, Cambridge, MA
Property

Office

120,000 SF
Availability

1 Space

5,507 SF
Year Built

1987
For Lease Contact for pricing
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55 Cambridge Pkwy

55 Cambridge Pkwy, East Cambridge, Cambridge, MA
Property

Office

275,968 SF
Availability

1 Space

1,996 SF
Year Built

1985
For Lease Contact for pricing
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Urban Warehouse Space

293 Cambridge St, East Cambridge, Cambridge, MA
Property

Office

3,171 SF
Availability

1 Space

3,171 SF
Year Built

1929
For Lease Contact for pricing
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55 Cambridge Parkway

55 Cambridge Parkway, East Cambridge, Cambridge, MA
Property

Office

283,311 SF
Availability

8 Spaces

128,889 SF
Year Built

1985
For Lease Contact for pricing
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31 Walden Street

31 Walden Street, North Cambridge, Cambridge, MA
Property

Multi-Family

5,120 SF
Year Built

1871
For Sale

$2,950,000
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1132 Cambridge Street

1132 Cambridge St, Inman/ Harrington, Cambridge, MA
Property

Retail

3,024 SF
Availability

1 Space

1,763 SF
Year Built

1890
For Lease

$7,500.00/MO
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Alexandria Center at Kendall Square

100 Binney St, East Cambridge, Cambridge, MA
Property

Unassigned

431,500 SF
Availability

1 Space

22,383 SF
Year Built

2018
For Lease

$105.00/SF/YR
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625 Massachusetts Avenue
WeWork
625 Massachusetts Avenue, Cambridge, MA
Services

Open Workspace

Event Space

Meeting Room

Private Office

Dedicated Desk
Amenities

Bike storage

Complimentary coffee & tea

Ethernet

Free water

High-speed wifi

IT support

Kitchen

Lounge area

Office supplies

Paper shredding services
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Kendall Center - 255 Main Street

255 Main Street, MIT, Cambridge, MA
Property

Office

215,629 SF
Availability

3 Spaces

37,591 SF
Year Built

1987
For Lease Contact for pricing
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RINDGE COMMONS

430 Rindge Ave, North Cambridge, Cambridge, MA
Property

Office

5,090 SF
Availability

1 Space

5,090 SF
Year Built

2024
For Lease Contact for pricing
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2329 Massachusetts Avenue

2329 Massachusetts Avenue, North Cambridge, Cambridge, MA
Property

Office

6,256 SF
Availability

1 Space

650 SF
Year Built

1960
For Lease

$35.00/SF/YR
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1430 Massachusetts Ave

1430 Massachusetts Ave, West Cambridge, Cambridge, MA
Property

Retail

32,528 SF
Availability

3 Spaces

16,667 SF
Year Built

1890
For Lease Contact for pricing
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164 Sidney Street

164 Sidney Street, Cambridgeport, Cambridge, MA
Property

Office

1,000 SF
Availability

1 Space

1,000 SF
For Lease

$1.00/SF/YR
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26 New Street

26 New Street, Peabody, Cambridge, MA
Property

Office

16,700 SF
Availability

1 Space

3,000 SF
For Lease Contact for pricing
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Chapman Arms

4 University Road, West Cambridge, Cambridge, MA
Property

Office

59,175 SF
Availability

2 Spaces

3,561 SF
For Lease Contact for pricing
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Cambridge Discovery Park - Building 100

100 Acorn Park Drive, North Cambridge, Cambridge, MA
Property

Office

128,601 SF
Availability

3 Spaces

60,108 SF
Year Built

2005
For Lease Contact for pricing
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Forty Thorndike

40 Thorndike Street, East Cambridge, Cambridge, MA
Property

Office

500,000 SF
Availability

3 Spaces

7,644 SF
Year Built

2024
For Lease Contact for pricing
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150 Columbia St

150 Columbia St, Area 4, Cambridge, MA
Property

Retail

7,088 SF
Availability

2 Spaces

2,201 SF
Year Built

1890
For Lease

$45.00/SF/YR
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53 Smith Place

53 Smith Place , Cambridge Highlands, Cambridge, MA
Property

Industrial

6,642 SF
For Sale

Subject To Offer
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LabCentral 238

238 Main Street, MIT, Cambridge, MA
Property

Office

414,000 SF
Availability

2 Spaces

12,825 SF
Year Built

2021
For Lease Contact for pricing
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Building 400/500

20-30 Acorn Park Drive, North Cambridge, Cambridge, MA
Property

Unassigned

270,000 SF
Availability

1 Space

26,349 SF
Year Built

2020
For Lease

$85.00/SF/YR
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1035 Cambridge Street

1035 Cambridge Street, Inman/ Harrington, Cambridge, MA
Property

Office

120,000 SF
Availability

1 Space

2,714 SF
Year Built

1988
For Lease Contact for pricing
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Central Plaza

675 Massachusetts Avenue, Mid-Cambridge, Cambridge, MA
Property

Office

208,458 SF
Availability

4 Spaces

18,406 SF
Year Built

1961
For Lease Contact for pricing
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75 Binney Street

75 Binney Street, East Cambridge, Cambridge, MA
Property

Office

151,160 SF
Availability

2 Spaces

124,180 SF
Year Built

2015
For Lease

$40.00 - $70.00/SF/YR
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610 Main St - North

610 Main St - North, Area 4, Cambridge, MA
Property

Unassigned

229,230 SF
Availability

1 Space

65,376 SF
Year Built

2016
For Lease

$100.00/SF/YR
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1050 Massachusetts Ave

1050 Massachusetts Ave, Riverside, Cambridge, MA
Property

Office

63,632 SF
Availability

1 Space

14,959 SF
Year Built

1979
For Lease Contact for pricing
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872 Massachusetts Ave

872 Massachusetts Ave, Riverside, Cambridge, MA
Property

Office

20,000 SF
For Sale

Subject To Offer
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222 Third

222 3rd Street, East Cambridge, Cambridge, MA
Property

Office

114,364 SF
Availability

1 Space

3,597 SF
Year Built

1918
For Lease Contact for pricing
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55 Cambridge Parkway

55 Cambridge Parkway, East Cambridge, Cambridge, MA
Property

Office

275,968 SF
Availability

1 Space

6,144 SF
Year Built

1985
For Lease Contact for pricing
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1 Canal Park

1 Canal Park, East Cambridge, Cambridge, MA
Property

Unassigned

104,910 SF
Availability

1 Space

68,720 SF
Year Built

2023
For Lease Contact for pricing
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Frequently Asked Questions

Commercial real estate is a broad category that includes a high variety of space types designed to meet the needs of various industries of the local economy and their specialized subsectors, as presented in our real estate 101 guide to types of commercial real estate. However, there are three main categories that you are most likely to come across: office, retail, and industrial space.

Modern office space is typically organized over large floor plates bound by high ceilings and large windows for an abundance of natural light and is located in transit-oriented developments with good access to multiple modes of transportation, so as to facilitate employee commute. The Cambridge commercial real estate market incorporates 5,795,618 square feet of office space across 59 buildings.

Office buildings can also accommodate coworking spaces, which are shared office options that typically cater to the needs of small, startup businesses that require flexible workspaces, a concentration of amenities, and services that can be accessed on an occasional or short-term basis. In Cambridge, the coworking segment of the commercial real estate market incorporates about 749 square feet.
Retail space includes shopping malls, department stores, street retail, or specialty stores dedicated to a narrow range of products. Such properties are typically located in high foot-traffic and/or car traffic areas, to facilitate customer access. The Cambridge commercial real estate market includes 577,523 square feet of retail space in a variety of settings.
Industrial property most often serves businesses operating in manufacturing or logistics and generally consists of large open spaces located within good access to roads, railways, freight airports or regional water ports. Industrial space listings can include warehouses, manufacturing plants, distribution centers, flexible industrial space, or even data center facilities. Across the Cambridge market, there is a total of 6,642 square feet of industrial property.

The listing inventory in Cambridge incorporates commercial real estate for lease and for sale of almost all property types and subtypes. However, you’ll find some categories offer more rental or investment opportunities than others.

The largest share of commercial real estate space for lease in Cambridge is represented by Office space, which accounts for 1,613,507 square feet of available listings. Retail space available in Cambridge adds up to 98,008 square feet.

Meanwhile, most of the listings of commercial property for sale in Cambridge are in the Office category.

The price of renting or buying commercial real estate is influenced by a variety of factors, including: the property type (for example, office space is priced higher than other property types in most locations); the condition and asset class rating (property rated class A or above will typically command a higher price than lower grade classifications); the quality or the development potential of the property location; whether or not there is high demand for the type of commercial asset in question; and what the state of supply is relative to demand.

The average rent for commercial real estate space listed for lease in Cambridge is $48.67 per square foot. However, this value does not offer enough perspective on its own, as you will find significant variation in prices across property types, property classes, and location, as well as other impacting factors. For instance, rent per square foot of office space in Cambridge can vary greatly depending on the rating of the property from Class A to Class C, as well as across the city depending on the location of the asset.

Whether you are looking for commercial real estate for lease or commercial property for sale, the best choice of location depends on the factors that are most relevant to your business strategy. A good thing to look for at the start, however, is the areas of the city that have the highest concentration of your preferred type of property, as these areas are generally well connected to the amenities and points of interest that are most relevant to each property type.

As such, there are several areas that you could consider to be the best location for commercial real estate in Cambridge, depending on the property type you are interested in. The highest concentration of commercial space listings of any kind in Cambridge is in the East Cambridge neighborhood. But if we look at each commercial property type, we find that for office space, the best location is the East Cambridge area.

Meanwhile, retail space opportunities are most abundant in the East Cambridge submarket. Alternatively, if you are looking for warehouse or other industrial space, consider looking at listings in Cambridge Highlands.

Select your preferred property type from the search filters menu at the top of the search page and then navigate the interactive map for a better view of commercial real estate availability in the locations most suited to your needs.

Regardless of whether buying or leasing commercial space is a new experience for you, there are significant benefits to working with a commercial real estate broker. In addition to saving you time and money, an experienced broker will contribute specialist knowledge of the local market, the property type you need representation for, and will handle negotiations on your behalf in your best interest.

To start, it is important for you to have a good understanding of what kind of broker you need. For instance, there are differences between a tenant broker and a listing broker. Also important at the start is to have a clear idea of what kind of space (or tenant) you are looking for and what (if any) particular needs and requirements you might have. And, while it is good to get a referral, you should interview several brokers to better gauge who you feel would best represent your interests.

CommercialCafe hosts listings from some of the most trusted commercial real estate brokerages in the country. Use the contact form available on each listing page or the contact details for the property representatives to reach out and start your search!

The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself — which itself includes aspects such as location, property class, amenities, and the quality of the property management — to the local market conditions, the state of the local economy, the demand for that particular type of commercial property, and of course the costs of owning and maintaining it relative to what leasing rate or sale price you get from the property. Asking rents in the city went as high as $85 per square foot.

Conversely, the highest sale price last year was $99,000,000 that is located at 790 Memorial Drive.

The average size of a commercial property in Cambridge depends greatly on the property type and the location — geographical possibilities and zoning allowances have significant influence on how big developers can build. While there are outliers that break height or volume records in the city, we can look at some average sizes by property use:

In Cambridge, the average size of an office property is 103,494 square feet.
Retail properties here incorporate an average of 36,096 square feet.
Industrial space in Cambridge is in buildings that are, on average 6,642 square feet in size.

Cambridge, MA Currently Available Listings

Commercial Space for Lease Breakdown

Commercial real estate listings for rent in Cambridge currently add up to 1,807,669 square feet. The market offers 57 active office listing(s), which amount to 1,645,739 square feet and account for 71% of commercial spaces on the market. Local retail availability includes 107,782 square feet across 22 retail space(s).

Property Type	Count of Listings	Total SF
Office	57	1,645,739
Retail	22	107,782
Other	1	54,148

Commercial Space for Sale Breakdown

What’s more, if you are interested in making an investment in the local market, you can also find commercial real estate for sale in Cambridge, MA. Currently, there is 46,711 square feet of commercial property for sale here , which includes 1 office building(s) for sale , 2 retail investment opportunity listing(s) , and 1 listing(s) of industrial real estate property for sale .

Property Type	Count of Listings	Total SF
Office	1	20,000
Retail	2	12,618
Industrial	1	6,642
Other	4	7,451

Cambridge, MA Commercial Real Estate Market Overview

Cambridge has a robust and diverse economy fueled by a host of major medical, biotech, and pharmaceutical companies, as well as its high concentration of successful startups originating in Kendall Square.

Home to both Harvard and MIT, the city boasts an impressive talent pool. As a result, companies such as Pfizer, Sanofi and Novartis — as well as nonprofit groups and think tanks, such as the Lincoln Institute of Land Policy, the National Bureau of Economic Research and the Smithsonian Astrophysical Observatory — drive the demand for commercial real estate properties in Cambridge.

Public transit in Cambridge is handled by the Massachusetts Bay Transportation Authority (MBTA), which operates an underground rapid transit system, buses and commuter rail networks, as well as water shuttles. The city also is serviced by the Charles River Transportation Management Agency (CRTMA). U.S. Route 1 and I-93, Route 2, Route 16 and the McGrath Highway (Route 28) also provide access into Cambridge.

Cambridge, MA Commercial Real Estate for Lease and Sale

Frequently Asked Questions

What are the different types of commercial real estate?

What types of commercial real estate are available in Cambridge, MA?

What factors affect the price of commercial real estate in Cambridge, MA?

What is the average rent for commercial space in Cambridge, MA?

What are the best areas for commercial real estate in Cambridge, MA?

How do I find a good commercial real estate broker?

What is the most profitable commercial real estate?

What is the average size of a commercial property in Cambridge, MA?

Cambridge, MA Currently Available Listings

Commercial Space for Lease Breakdown

Commercial Space for Sale Breakdown

Cambridge, MA Commercial Real Estate Market Overview

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