Durham, NC Commercial Real Estate for Lease and Sale

Explore 270 listings of Durham commercial real estate to find the best space for your business.

3718 North Roxboro Street

3718 N Roxboro Street, Summer Meadow, Durham, NC
Property

Retail

1,943 SF
Availability

1 Space

1,943 SF
For Lease

$45.00/SF/YR
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4601 Research Commons

4601 Research Commons, Research Triangle Park, Durham, NC
Property

Office

422,483 SF
Availability

5 Spaces

137,539 SF
Year Built

1985
For Lease

$35.00 - $37.50/SF/YR
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3105 Colclough Ave and 3101 Bundy Ave

3105 Colclough Ave and 3101 Bundy Ave, Crown Point, Durham, NC
Property

Other

12.83 Acre
For Sale

$1,700,000
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Homestead Market

105 West State Highway 54, Darby Glen, Durham, NC
Property

Retail

165,000 SF
Availability

1 Space

1,440 SF
Year Built

1988
For Lease Contact for pricing
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Lynn Road and Holloway Street

Lynn Road and Holloway Street, Amberlynn Valley, Durham, NC
Property

VacantLand

2.06 Acre
Availability

1 Space

2.06 Acre
For Lease Contact for pricing
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Research Tri-Center South V & VI

3791 South Alston Avenue, Research Triangle Park, Durham, NC
Property

Industrial

281,101 SF
Availability

1 Space

108,830 SF
Year Built

1997
For Lease Contact for pricing
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Welcome Venture Park

1325 Hamlin Rd, Falls Lake, Durham, NC
Property

Industrial
Availability

1 Space

394,800 SF
Year Built

2024
For Lease Contact for pricing
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125 Orange St

125 Orange St, Central Park, Durham, NC
Property

Retail

4,188 SF
Availability

2 Spaces

4,188 SF
Year Built

1900
For Lease Contact for pricing
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Patriot Park 3

5 National Way, Research Triangle Park, Durham, NC
Property

Industrial

187,500 SF
Availability

1 Space

187,500 SF
Year Built

2020
For Lease Contact for pricing
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1910 Sedwick Rd

1910 Sedwick Rd, Audubon Park, Durham, NC
Property

Office

6,232 SF
Availability

5 Spaces

4,730 SF
Year Built

1984
For Lease

$18.00 - $20.00/SF/YR
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Frequently Asked Questions

Commercial real estate is a broad category that includes a high variety of space types designed to meet the needs of various industries of the local economy and their specialized subsectors, as presented in our real estate 101 guide to types of commercial real estate. However, there are three main categories that you are most likely to come across: office, retail, and industrial space.
- Modern office space is typically organized over large floor plates bound by high ceilings and large windows for an abundance of natural light and is located in transit-oriented developments with good access to multiple modes of transportation, so as to facilitate employee commute. The Durham commercial real estate market incorporates 13,753,909 square feet of office space across 141 buildings.
  
  Office buildings can also accommodate coworking spaces, which are shared office options that typically cater to the needs of small, startup businesses that require flexible workspaces, a concentration of amenities, and services that can be accessed on an occasional or short-term basis.
- Retail space includes shopping malls, department stores, street retail, or specialty stores dedicated to a narrow range of products. Such properties are typically located in high foot-traffic and/or car traffic areas, to facilitate customer access. The Durham commercial real estate market includes 2,971,611 square feet of retail space in a variety of settings.
- Industrial property most often serves businesses operating in manufacturing or logistics and generally consists of large open spaces located within good access to roads, railways, freight airports or regional water ports. Industrial space listings can include warehouses, manufacturing plants, distribution centers, flexible industrial space, or even data center facilities. Across the Durham market, there is a total of 1,139,003 square feet of industrial property.
The listing inventory in Durham incorporates commercial real estate for lease and for sale of almost all property types and subtypes. However, you’ll find some categories offer more rental or investment opportunities than others.

The largest share of commercial real estate space for lease in Durham is represented by Office space, which accounts for 4,955,848 square feet of available listings. Industrial space available in Durham adds up to 1,498,769 square feet.

Meanwhile, most of the listings of commercial property for sale in Durham are in the Office category.
The price of renting or buying commercial real estate is influenced by a variety of factors, including: the property type (for example, office space is priced higher than other property types in most locations); the condition and asset class rating (property rated class A or above will typically command a higher price than lower grade classifications); the quality or the development potential of the property location; whether or not there is high demand for the type of commercial asset in question; and what the state of supply is relative to demand.
The average rent for commercial real estate space listed for lease in Durham is $26.31 per square foot. However, this value does not offer enough perspective on its own, as you will find significant variation in prices across property types, property classes, and location, as well as other impacting factors. For instance, rent per square foot of office space in Durham can vary greatly depending on the rating of the property from Class A to Class C, as well as across the city depending on the location of the asset.
Whether you are looking for commercial real estate for lease or commercial property for sale, the best choice of location depends on the factors that are most relevant to your business strategy. A good thing to look for at the start, however, is the areas of the city that have the highest concentration of your preferred type of property, as these areas are generally well connected to the amenities and points of interest that are most relevant to each property type.

As such, there are several areas that you could consider to be the best location for commercial real estate in Durham, depending on the property type you are interested in. The highest concentration of commercial space listings of any kind in Durham is in the Research Triangle Park neighborhood. But if we look at each commercial property type, we find that for office space, the best location is the Research Triangle Park area.

Meanwhile, retail space opportunities are most abundant in the Old North Durham submarket. Alternatively, if you are looking for warehouse or other industrial space, consider looking at listings in Research Triangle Park.

Select your preferred property type from the search filters menu at the top of the search page and then navigate the interactive map for a better view of commercial real estate availability in the locations most suited to your needs.
Regardless of whether buying or leasing commercial space is a new experience for you, there are significant benefits to working with a commercial real estate broker. In addition to saving you time and money, an experienced broker will contribute specialist knowledge of the local market, the property type you need representation for, and will handle negotiations on your behalf in your best interest.

To start, it is important for you to have a good understanding of what kind of broker you need. For instance, there are differences between a tenant broker and a listing broker. Also important at the start is to have a clear idea of what kind of space (or tenant) you are looking for and what (if any) particular needs and requirements you might have. And, while it is good to get a referral, you should interview several brokers to better gauge who you feel would best represent your interests.

CommercialCafe hosts listings from some of the most trusted commercial real estate brokerages in the country. Use the contact form available on each listing page or the contact details for the property representatives to reach out and start your search!
The profitability of a commercial real estate investment depends on a multitude of factors working together. These factors include the quality of the asset itself — which itself includes aspects such as location, property class, amenities, and the quality of the property management — to the local market conditions, the state of the local economy, the demand for that particular type of commercial property, and of course the costs of owning and maintaining it relative to what leasing rate or sale price you get from the property. Asking rents in the city went as high as $33.5 per square foot. In particular, the property type commanding the highest lease rates in Durham was Office space.

Conversely, the highest sale price last year was $73,500,000 that is located at 300 North Duke Street.
The average size of a commercial property in Durham depends greatly on the property type and the location — geographical possibilities and zoning allowances have significant influence on how big developers can build. While there are outliers that break height or volume records in the city, we can look at some average sizes by property use:
- In Durham, the average size of an office property is 101,132 square feet.
- Retail properties here incorporate an average of 67,537 square feet.
- Industrial space in Durham is in buildings that are, on average 81,358 square feet in size.

Durham, NC Currently Available Listings

Commercial Space for Lease Breakdown

Commercial real estate listings for rent in Durham currently add up to 7,806,057 square feet. The market offers 128 active office listing(s), which amount to 4,925,278 square feet and account for 63% of commercial spaces on the market. Local retail availability includes 321,317 square feet across 45 retail space(s). Industrial space for rent opportunities in Durham amount to 1,658,861 square feet across a total of 19 warehouse and other industrial listing(s).

Property Type	Count of Listings	Total SF
Office	128	4,925,278
Retail	45	321,317
Industrial	19	1,658,861
Other	10	900,601

Commercial Space for Sale Breakdown

What’s more, if you are interested in making an investment in the local market, you can also find commercial real estate for sale in Durham, NC. Currently, there is 283,145 square feet of commercial property for sale here , which includes 11 office building(s) for sale , 5 retail investment opportunity listing(s) , and 2 listing(s) of industrial real estate property for sale .

Property Type	Count of Listings	Total SF
Office	11	144,828
Retail	5	30,671
Industrial	2	53,897
Other	33	53,749

Durham, NC Commercial Real Estate Market Overview

The City of Durham is strategically located in the heart of North Carolina, thanks to Bartlett S. Durham — the man who donated his land for a railroad station, which laid the city’s initial foundation. At first, Durham thrived as a hub for the tobacco industry. Today, the city is a confluence of education, creativity, industry and innovation. Commercial real estate in Durham serves a diverse economy in which technology, healthcare and education are the main industries.

Along with Raleigh and Chapel Hill, Durham makes up what is commonly referred to as The Triangle — Raleigh-Durham-Chapel Hill Research Triangle Park or RTP for short — a high-tech research and development center that has greatly revitalized the region following deindustrialization. In addition to research and development, local commercial inventory caters to manufacturing activity; logistical and storage enterprise; and business services firms. Moreover, the several notable institutions of higher education located in the city produce a steady outflow of highly skilled talent, giving Durham one of the most concentrated STEM labor pools in the country.

About us

CommercialCafe is your go-to commercial real estate listing source. We partner with highly respected major brokerages from across the country to ensure high-quality listings that are updated frequently. Our online marketplace lists all commercial property types from office, coworking, retail, and industrial to special purpose properties.

CommercialCafe is a trusted Yardi brand and is an integral part of the CommercialEdge network — the fastest-growing network of online real estate marketplaces, which ranks on the 1st page of Google for all top markets, attracts more than 2 million monthly visits, and generates more than 350,000 broker contacts.

Durham, NC Commercial Real Estate for Lease and Sale

3718 North Roxboro Street

4601 Research Commons

3105 Colclough Ave and 3101 Bundy Ave

Homestead Market

Lynn Road and Holloway Street

Research Tri-Center South V & VI

Welcome Venture Park

125 Orange St

Patriot Park 3

1910 Sedwick Rd

Frequently Asked Questions

Durham, NC Currently Available Listings

Commercial Space for Lease Breakdown

Commercial Space for Sale Breakdown

Durham, NC Commercial Real Estate Market Overview

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Durham, NC Commercial Real Estate for Lease and Sale

Frequently Asked Questions

What are the different types of commercial real estate?

What types of commercial real estate are available in Durham, NC?

What factors affect the price of commercial real estate in Durham, NC?

What is the average rent for commercial space in Durham, NC?

What are the best areas for commercial real estate in Durham, NC?

How do I find a good commercial real estate broker?

What is the most profitable commercial real estate?

What is the average size of a commercial property in Durham, NC?

Durham, NC Currently Available Listings

Commercial Space for Lease Breakdown

Commercial Space for Sale Breakdown

Durham, NC Commercial Real Estate Market Overview

Other Popular Searches

Popular Coworking Searches

Popular Office Searches

Popular Retail Searches

Popular Industrial Searches

About us