San Diego, CA Office Spaces for Rent

Find your best San Diego, CA office space among 1,666 for rent listings, which average an asking price of $41.6 per square foot.

Office Market FAQs

3770 4th Ave

3770 4th Ave, Hillcrest, San Diego, CA
Property

Office

2,840 SF
Availability

1 Space

2,840 SF
For Lease Contact for pricing
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Rancho Bernardo Heights

15717 Bernardo Heights Pkwy, Rancho Bernardo, San Diego, CA
Property

Retail

4,882 SF
Availability

2 Spaces

4,882 SF
Year Built

1984
For Lease Contact for pricing
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The Campus at Horton - Bldg. 600

300 Horton Plz., Horton Plaza, San Diego, CA
Property

Office

37,932 SF
Availability

1 Space

37,932 SF
Year Built

2024
For Lease Contact for pricing
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Medical Park with Waterfront Location

Liberty Station - 2790 Truxtun Road San Diego, Midway, San Diego, CA
Property

Office
Availability

1 Space

3,802 SF
For Lease Contact for pricing
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10717 Sorrento Valley Rd

10717 Sorrento Valley Rd, Torrey Pines Preserve, San Diego, CA
Property

Office

16,126 SF
Availability

1 Space

8,000 SF
Year Built

1987
For Lease

$3.25/SF/MO
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Bernardo North Business Center

11305 - 11315 Rancho Bernardo Road, Rancho Bernardo, San Diego, CA
Property

Office
Availability

1 Space

4,843 SF
For Lease Contact for pricing
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Daley Office Plaza III

4499 Ruffin Rd, Kearny Mesa, San Diego, CA
Property

Office

19,390 SF
Availability

2 Spaces

2,865 SF
Year Built

1989
For Lease Contact for pricing
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1510 Front St

1510 Front St, Little Italy, San Diego, CA
Property

Office

14,441 SF
Availability

5 Spaces

13,409 SF
Year Built

1984
For Lease

$2.10/SF/MO
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Towne Center

1706 5th Ave, Bankers Hill - Park West, San Diego, CA
Property

Office

14,333 SF
Availability

4 Spaces

3,978 SF
Year Built

1981
For Lease

$1.90/SF/MO
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4451-4453 30th Street

4451-4453 30TH ST, North Park, San Diego, CA
Property

Office

10,674 SF
Availability

1 Space

10,674 SF
For Lease Contact for pricing
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2222 Verus St

2222 Verus St, Palm City, San Diego, CA
Property

Industrial

15,865 SF
Availability

2 Spaces

11,729 SF
Year Built

1985
For Lease

$1.50 - $1.60/SF/MO
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The Presidio

5261-5401 Linda Vista Road, Morena, San Diego, CA
Property

Retail

14,263 SF
Availability

3 Spaces

12,937 SF
For Lease Contact for pricing
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Building K

6030 Village Way, Carmel Valley, San Diego, CA
Property

Office

7,619 SF
Availability

1 Space

7,619 SF
For Lease Contact for pricing
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Two Governor Park

6310 Greenwich Dr, University City, San Diego, CA
Property

Office

23,000 SF
Availability

1 Space

2,155 SF
Year Built

1985
For Lease Contact for pricing
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1515 2nd Ave.

1515 2nd Ave., Cortez, San Diego, CA
Property

Office

25,740 SF
Availability

3 Spaces

25,740 SF
Year Built

1986
For Lease Contact for pricing
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Mission Grove Office Park

1545 Hotel Circle South, Mission Valley West, San Diego, CA
Property

Office

65,649 SF
Availability

7 Spaces

20,638 SF
Year Built

1984
For Lease

$60,036.00/SF/YR
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Moda Sorrento

5502 Oberlin Drive, Sorrento Valley, San Diego, CA
Property

Office

25,806 SF
Availability

1 Space

25,806 SF
For Lease Contact for pricing
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Cornerstone Court

6155 Cornerstone Ct E, Sorrento Valley, San Diego, CA
Property

Office
Availability

4 Spaces

19,467 SF
For Lease Contact for pricing
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Scripps Lake Office Plaza

9810 Scripps Lake Dr, Scripps Ranch, San Diego, CA
Property

Office

13,628 SF
Availability

3 Spaces

7,033 SF
Year Built

2008
For Lease

$2.15 - $2.35/SF/MO
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Coastal Collection at Torrey Reserve - 11375 El Camino Real

11375 El Camino Real, Torrey Hills, San Diego, CA
Property

Office

15,784 SF
Availability

2 Spaces

15,784 SF
For Lease Contact for pricing
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Stadium Office Park II

3456 Camino Del Rio N, Mission Valley East, San Diego, CA
Property

Office

17,175 SF
Availability

1 Space

2,143 SF
Year Built

1975
For Lease

$2.15/SF/MO
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9560 Candida St

9560 Candida St, Miramar, San Diego, CA
Property

Industrial

8,373 SF
Availability

1 Space

120 SF
Year Built

1971
For Lease

$4.58/SF/MO
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Fairmount Business Park

10981 San Diego Mission Rd, Grantville, San Diego, CA
Property

Office

21,170 SF
Availability

3 Spaces

5,532 SF
For Lease

$1.90 - $2.05/SF/MO
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6342 Ferris Sq

6342 Ferris Sq, Sorrento Valley, San Diego, CA
Property

Office

5,788 SF
Availability

2 Spaces

5,788 SF
Year Built

1987
For Lease Contact for pricing
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The Preserve at Torrey Highlands - Bldg. 1

Camino Del Sur, Rancho Penasquitos, San Diego, CA
Property

Office

180,000 SF
Availability

1 Space

180,000 SF
Year Built

2035
For Lease Contact for pricing
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Elevation

16701-16725 W Bernardo Dr, Rancho Bernardo, San Diego, CA
Property

Office

148,747 SF
Availability

4 Spaces

148,323 SF
For Lease Contact for pricing
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Old Town Professional Building

2356 Moore St, Old Town San Diego, San Diego, CA
Property

Office

12,046 SF
Availability

2 Spaces

2,323 SF
Year Built

1977
For Lease

$2.25/SF/MO
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Metrocall Building

7380 Clairemont Mesa Blvd, Kearny Mesa, San Diego, CA
Property

Office

20,690 SF
Availability

1 Space

2,489 SF
Year Built

1973
For Lease

$2.05/SF/MO
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The Bluffs

16870 W Bernardo Drive, Rancho Bernardo, San Diego, CA
Property

Office
Availability

1 Space

10,515 SF
For Lease Contact for pricing
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1001 Garnet Avenue
VentureBeach Cowork
1001 Garnet Avenue #200, San Diego, CA
Services

Open Workspace

Meeting Room

Private Office
Amenities

Complimentary coffee & tea

Free water

Heating & A/C

High-speed internet

High-speed wifi

Kitchen

Lockers

Mail services

Office furniture

Parking
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6863 Friars Rd

6863 Friars Rd, Mission Valley West, San Diego, CA
Property

Office

20,259 SF
Availability

6 Spaces

19,615 SF
Year Built

1982
For Lease

$1.49/SF/MO
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9800 & 9855 Summers Ridge Road

9800 Summers Ridge Road, Sorrento Valley, San Diego, CA
Property

Office

618,000 SF
Availability

6 Spaces

618,000 SF
For Lease Contact for pricing
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La Jolla Commons III

4727 Executive Dr., University City, San Diego, CA
Property

Office

200,405 SF
Availability

1 Space

8,149 SF
Year Built

2023
For Lease

$64.20/SF/YR
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4875-4879 Viewridge Ave

4875-4879 Viewridge Ave, Kearny Mesa, San Diego, CA
Property

Office

16,600 SF
Availability

1 Space

8,406 SF
Year Built

1982
For Lease Contact for pricing
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Arvco Building

4655 Cass St, Pacific Beach, San Diego, CA
Property

Office

31,712 SF
Availability

2 Spaces

525 SF
For Lease

$3.08 - $3.17/SF/MO
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Moda Sorrento

5550 Oberlin Dr, Sorrento Valley, San Diego, CA
Property

Office

22,399 SF
Availability

2 Spaces

22,940 SF
Year Built

1984
For Lease Contact for pricing
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7270 Trade St

7270 Trade St, Miramar, San Diego, CA
Property

Office

20,152 SF
Availability

2 Spaces

9,820 SF
Year Built

2004
For Lease Contact for pricing
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4425 Bayard Street

4425 Bayard Street, Pacific Beach, San Diego, CA
Property

Office

9,720 SF
Availability

2 Spaces

2,648 SF
Year Built

1989
For Lease

$2.95 - $3.75/SF/MO
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7808 Clairemont Mesa Blvd

7808 Clairemont Mesa Blvd, Kearny Mesa, San Diego, CA
Property

Office

11,794 SF
Availability

1 Space

6,000 SF
Year Built

1975
For Lease Contact for pricing
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9276 Scranton Road
BioLabs
9276 Scranton Road #500 & 600, San Diego, CA
Services

Open Workspace

Event Space

Meeting Room

Private Office
Amenities

Complimentary coffee & tea

Concierge

High-speed internet

Kitchen

Mail services

Office furniture

On-site café

Printer

Privacy booths

Professional & social events
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1005 Rosecrans St

1005 Rosecrans St, La Playa, San Diego, CA
Property

Retail

5,954 SF
Availability

2 Spaces

2,079 SF
Year Built

2010
For Lease

$3.25 - $39.00/SF/YR
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11189 Sorrento Valley Rd, Suite 104

11189 Sorrento Valley Rd, Torrey Pines Preserve, San Diego, CA
Property

Office
Availability

1 Space

4,550 SF
For Lease Contact for pricing
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1925 Euclid Avenue
Oak Park Place
1925 Euclid Avenue, San Diego, CA
Services

Open Workspace

Meeting Room

Private Office

Dedicated Desk
Amenities

Business address

Complimentary coffee & tea

Free water

Heating & A/C

High-speed internet

High-speed wifi

Kitchen

Lounge area

Mail services

Natural light
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6760 Top Gun St

6760 Top Gun St, Sorrento Valley, San Diego, CA
Property

Office

24,750 SF
Availability

1 Space

12,140 SF
Year Built

1999
For Lease

$2.25/SF/MO
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SD Tech by Alexandria - Bldg. 4

9805 Scranton Rd., Sorrento Valley, San Diego, CA
Property

Office

111,084 SF
Availability

2 Spaces

111,084 SF
Year Built

1981
For Lease Contact for pricing
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The Campus at Horton - Bldg. 200

200 Horton Plz., Horton Plaza, San Diego, CA
Property

Office

204,842 SF
Availability

1 Space

204,842 SF
Year Built

2024
For Lease Contact for pricing
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4603 Mission Blvd

4603 Mission Blvd, Pacific Beach, San Diego, CA
Property

Retail

8,005 SF
Availability

2 Spaces

1,499 SF
Year Built

1985
For Lease Contact for pricing
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3980 9th Ave

3980 9th Ave #1, Hillcrest, San Diego, CA
Property

Office

1,706 SF
Availability

1 Space

1,706 SF
Year Built

2007
For Lease

$2.95/SF/MO
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3502 Kurtz Street

3502 Kurtz St, Midway, San Diego, CA
Property

Office

15,178 SF
Availability

1 Space

15,178 SF
Year Built

1987
For Lease

$1.65/SF/MO
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3356 - 3358 2ND AVENUE

3356 - 3358 2ND AVENUE , Bankers Hill - Park West, San Diego, CA
Property

Office

400 SF
Availability

2 Spaces

400 SF
For Lease Contact for pricing
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Del Rio Plaza

3703 Camino Del Rio S, Mission Valley East, San Diego, CA
Property

Office

22,595 SF
Availability

2 Spaces

11,049 SF
Year Built

1989
For Lease

$2.00 - $3.50/SF/MO
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La Jolla Reserve

4445 Eastgate Mall, University City, San Diego, CA
Property

Office

123,608 SF
Availability

1 Space

5,074 SF
Year Built

2000
For Lease

$12.00/SF/YR
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Frequently Asked Questions

Asking prices vary based on the property location, rating, amenities such as proximity to restaurants, cafes, and entertainment venues, as well as convenience of access to public transport, airports, and thoroughfares.

The average rent for office space in San Diego is $41.6 per square foot. The minimum rental rate for office space in San Diego is $3.95 per square foot. Among listings of office space currently available for lease in San Diego, the maximum rental rate is $192 per square foot.

The most common factor that influences cost of office space in any location is the property class rating. For example, San Diego office space rated Class A asks an average of $46.25 per square foot. Class B office space in San Diego costs $36.44 per square foot, on average. Listings of office space in Class C buildings asked an average of $24.72 per square foot.

For more details on San Diego office space rent and sales prices, as well as overall market quality and new construction data, see San Diego Office Market Trends.

Most experts recommend an average of between 75 and 150 square feet of office space per person. However, it is important to keep in mind that how much office space you ultimately need depends on your activity and how you need to use the space, as much as it does on how many people it should accommodate. If you already know what size office would best suit your needs, use the available space size filter at the top of the search page to focus your search on the best fit for you.

You’ll find a home for almost any size of business in San Diego, as the local office market offers a wide range of options. Office spaces currently on the market go up to as much as 450,000 square feet in size for an individual listing.
However, there is a variety of differently sized opportunities below that maximum. For your consideration, the median size of an office space for lease in San Diego is 3,572 square feet, and the average office space size here is 9,141 square feet.

You can find 1,666 office listing(s) for lease in San Diego, which add up to a total of 15,406,350 square feet. Availability on the market includes a variety of office use types, such as General Office, Medical Office, Flex - Office, R&D - Office, Creative Office.

The most common office use type currently available for lease in San Diego is General Office, which is offered in 1,230 or 73.83% of listings. The second-most frequent office use type listed here is Medical Office, which account for 113 or 6.78% of office space currently available. On the other end of the spectrum, the office use type least common among local listings is Flex - Industrial, which is available in 1 listing(s).

You can search 103 office sublease listing(s) in San Diego, which amount to a total of 1,799,689 square feet. Sublease opportunities on the market include General Office, R&D - Office, Flex - Office. The San Diego neighborhood or submarket with the most sublease listings available is University City.

The best choice of neighborhood for your office space will greatly depend on the elements that are most relevant to your business and your employees. However, a good criterion to start with is to look at the areas of the city that have the highest concentration of office properties, as these areas are generally well connected to transit options and have a good degree of amenity availability.

In San Diego, the greatest concentration of office space for lease opportunities is in Core - Columbia, Mission Valley East, Kearny Mesa.

Each individual’s commuting experience will of course be different depending on a number of factors. Check the location description details for the office listings that catch your eye, to get an overview of walkability, access to public transport, the quality of infrastructure dedicated to biking commuters, as well as the proximity to parking facilities, fuel stations, and other essential amenities.

The San Diego office market incorporates a mix of properties of various ages, ratings, construction grades, and other quality indicators. Roughly 44.06% of total office space listings in the city are in properties rated Class A. You will find the highest concentration of Class A office space in the Core - Columbia neighborhood of San Diego. Class B office space accounts for 46.1% of spaces listed on the leasing market. The neighborhood with the most Class B office space is Kearny Mesa. Class C office space makes up 3.54% of office space available in San Diego.

Buildings completed in and since the year 2000 account for 23.63% of office properties in the city and incorporate a total of 14,174,916 square feet. About 2.32% of office space in San Diego is in buildings that have been renovated at least once since 2000.

Out of the office space listings currently available in San Diego, you can find 309 LEED-certified or LEED-proposed option(s). A total of 47 building(s) here earned a LEED-certification — certification levelPlatinum (3), Gold (29), Silver (13). The local market includes 3 LEED-proposed office building(s) awaiting certification in San Diego.

There are, of course, a lot of things to factor in when you are looking for office space. Aspects including the accessibility of the location, the quality of the facility, the size of the space, the convenience of nearby amenities, the type and duration of the lease, and of course the cost are all part of the search and decision process. For a quick checklist of what you should take into account when researching the market, consider these seven tips for choosing the best office location for your business. Alternatively, for a comprehensive take on everything to consider when looking for office space, see our in-depth guide to finding office space for small or growing companies. The guide also includes insights from seasoned professionals and can serve as a helpful resource for growing companies, no matter their current size.

Are you looking to lease office space in the vicinity of your current location or in a particular neighborhood of San Diego? Using the interactive map, you can easily navigate to your preferred location and customize your search area around a specific point of interest. Select “Radius” from the Search Mode options menu, click on the map to set your search reference point, and expand the radius to select your desired search area. Browse available listings to find the best office space that meets your location, as well as other business needs.

San Diego, CA Office Inventory Breakdown

There are a number of factors that make a city attractive for businesses to relocate or expand, as well as for investors to enhance their portfolios through local acquisitions. Among the most important factors to consider are the size and quality of the local office market, which is an essential component of the local economy.

Total Office Space in San Diego: 92,281,941 Sq. Ft.

In 2024 the San Diego office market encompassed 92,281,941 square feet of space. Out of that total, 4,730,541 square feet were in office properties sized between 500,000 and 1,000,000 square feet. Meanwhile, 23,105,214 square feet were in office buildings sized between 50,000 and 100,000 square feet.
Class A office space makes up a 49.77% share of San Diego office inventory, while Class B office assets represent roughly 45.51% of the market total.

San Diego Office Market Breakdown by Building Size
Building Size Range	Total Square Feet	Share of Total Office
50k to 100k Sq. Ft.	23,105,214 Sq. Ft.	25.04%
100k to 500k Sq. Ft.	54,725,047 Sq. Ft.	59.3%
500k to 1M Sq. Ft.	4,730,541 Sq. Ft.	5.13%

San Diego Office Market Breakdown by Building Quality Rating
Class	Total Square Feet	Share of Total Office
Class A+	2,610,747 Sq. Ft.	2.83%
Class A	45,927,011 Sq. Ft.	49.77%
Class B	41,992,960 Sq. Ft.	45.51%
Class C	1,751,223 Sq. Ft.	1.9%

Data was provided by CommercialEdge, refers to properties larger than 50,000 square feet.

San Diego, CA Office Market Overview

San Diego, Calif., is the eighth-largest city in the U.S. and the second-largest in California, as well as part of the San Diego-Tijuana conurbation, which straddles the Mexican border. The city is famous for its sunny beaches, rich culture, vast U.S. Navy presence and talented workforce.

The main economic sectors in San Diego include military and defense, innovation, tourism, education and healthcare. Universities here — such as the University of California San Diego and San Diego State University — rank among the best in the nation for international business, and thousands of students here graduate with STEM degrees each year. San Diego is also one of the best cities in the country for Millennials to live and work.

With more and more businesses launching with the help of accelerators and incubators, demand for prime office in San Diego is strong. Nearly half of all San Diego office inventory is Class A.

Suburbs Home to 67% of All Offices Constructed in Last 20 Years

The very suburban markets of the Bay Area and San Diego added office space exactly there — in the suburbs. San Diego’s suburbs saw a whopping 91% of total office construction in the MSA — nearly 27 million square feet across 268 properties. Despite the fact that the dispersion of properties covered many of the outer regions of the San Diego market, the lion’s share of the properties were claimed by Carlsbad, Torrey Pines and the Sorrento Valley. That’s because San Diego’s biotechnology sector is largely concentrated in those submarkets — and they show no signs of slowing down. San Diego coworking has also been expanding recently.

Top 20 US Metros for Life Science Companies in 2022

12.3 million square feet of life sciences stock accounted for nearly 11% of the market — and the San Diego life sciences market is preparing for further growth: With 4.5 million square feet of new life sciences office projects in the pipeline, the San Diego metro area is looking at a market expansion of nearly 40% of its current stock.

Top Cities for Internet Connectivity & Speed

The biotech industry is prominent in San Diego, so WFH is definitely a possibility for its many residents. Notably, California as a state is actually 36th in the nation for speed. So, while many people are connected, the speeds aren’t quite up to par with the East Coast states

Flexible Workforce Demand Drives Growth of Coworking Sector

Notably, only two other markets saw their local listing rates grow by double digits during the same time frame: Listing rates for office space in San Diego and Boston increased 13.9% and 15.2% year-over-year, respectively.

2022’s Top 50 Most Expensive Office Sales

Further south, a portfolio sale of San Diego office spaces was just shy of the top 10 most expensive office transactions of 2022.

Office Pipeline 2023: Tight Race Between Manhattan & Boston for Top Spot

Block 2B — which ranked 16th among the largest projects in the U.S. office pipeline this year — will add some 765,000 square feet of new space to the San Diego market.

Artificial Intelligence in the U.S.: Top Innovators & Hottest Markets

San Diego was the last of the four California entries to rank among the 25 most innovative metros in the U.S., in no small part due to semiconductor and wireless communications technology manufacturer Qualcomm Technologies, Inc., which is headquartered here.

About us

CommercialCafe is your go-to commercial real estate listing source. We partner with highly respected major brokerages from across the country to ensure high-quality listings that are updated frequently. Our online marketplace lists all commercial property types from office, coworking, retail, and industrial to special purpose properties.

CommercialCafe is a trusted Yardi brand and is an integral part of the CommercialEdge network — the fastest-growing network of online real estate marketplaces, which ranks on the 1st page of Google for all top markets, attracts more than 2 million monthly visits, and generates more than 350,000 broker contacts.

San Diego, CA Office Spaces for Rent

Frequently Asked Questions

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