Saint Louis, MO Office Spaces for Rent

Find your best Saint Louis, MO office space among 246 for rent listings, which average an asking price of $24.6 per square foot.

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2027 Salisbury Street
Apiary @ The Park
2027 Salisbury Street, St. Louis, MO
Services

Meeting Room

Private Office

Dedicated Desk
Amenities

Complimentary coffee & tea

Free water

On-site café
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555 Washington Avenue
STL Fusion
555 Washington Avenue #310, St. Louis, MO
Services

Open Workspace

Event Space

Meeting Room

Private Office
Amenities

24/7 security

Beer

Breakfast

Cleaning services

Complimentary coffee & tea

Free water

High-speed internet

High-speed wifi

Mail services

Printer
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6 Cardinal Way
Spark
6 Cardinal Way #900, St. Louis, MO
Services

Virtual Office

Open Workspace

Meeting Room

Private Office

Dedicated Desk
Amenities

Beer

Bike storage

Catering

Complimentary coffee & tea

Concierge

High-speed wifi

Kitchen

Lounge area

Mother’s room

Parking
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2710 Lafayette Avenue
The Dreamer's Loft
2710 Lafayette Avenue, St. Louis, MO
Services

Open Workspace

Event Space

Meeting Room

Dedicated Desk
Amenities

Business address

High-speed wifi

Kitchen

Mail services

Mother’s room

Office supplies

Parking

Printer

Privacy booths

TV/Monitor
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911 Washington Avenue
T-REX
911 Washington Avenue, St. Louis, MO
Services

Open Workspace

Meeting Room

Private Office
Amenities

Complimentary coffee & tea

Espresso bar

Free water

Game room

High-speed wifi

Kitchen

Office furniture

Privacy booths

Professional & social events

TV/Monitor
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5850 Macklind Avenue
CoRadius Coworking
5850 Macklind Avenue, St. Louis, MO
Services

Open Workspace

Meeting Room

Private Office

Dedicated Desk
Amenities

Complimentary coffee & tea

High-speed wifi

Kitchen

Lockable filing cabinets

Mail services

Parking

Printer

Receptionist/Secretarial services

TV/Monitor
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3407 South Jefferson Avenue
Nebula
3407 South Jefferson Avenue, St. Louis, MO
Services

Virtual Office

Open Workspace

Meeting Room

Private Office

Dedicated Desk
Amenities

Beer

Bike storage

Complimentary coffee & tea

High-speed internet

High-speed wifi

Kitchen

Mail services

Natural light

Notary/Legal services

Parking
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3139 Olive Street
Heydays
3139 Olive Street, St. Louis, MO
Services

Open Workspace

Event Space
Amenities

Kitchen

Natural light

Patio

Projector
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614 N 11th St

614 N 11th St, Downtown Saint Louis, Saint Louis, MO
Property

Office

9,267 SF
Availability

3 Spaces

9,000 SF
Year Built

1905
For Lease Contact for pricing
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1010 Locust Street

1010 Locust Street, Downtown Saint Louis, St. Louis, MO
Property

Office

4,200 SF
Availability

1 Space

4,200 SF
For Lease

$15.25/SF/YR
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1808 Chouteau Ave

1808 Chouteau Ave, Lafayette Square, St. Louis, MO
Property

Office

950 SF
Availability

1 Space

950 SF
For Lease

$1,900.00/MO
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Spark St. Louis Coworking Space

6 Cardinal Way, Downtown Saint Louis, St. Louis, MO
Property

Office

5,416 SF
Availability

5 Spaces

4,316 SF
For Lease Contact for pricing
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Rock Spring School

3974 Sarpy Ave, Forest Park South East, St. Louis, MO
Property

Office

32,300 SF
Availability

15 Spaces

15,268 SF
Year Built

1898
For Lease

$27.00/SF/YR
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2300-2324 Marconi Avenue

2324 Marconi Avenue, The Hill, St. Louis, MO
Property

Industrial

95,023 SF
Availability

1 Space

5,000 SF
Year Built

1920
For Lease

$12.00/SF/YR
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210 N. 17th St.

210 N. 17th St., Downtown West Saint Louis, St. Louis, MO
Property

Office

1,100 SF
Availability

1 Space

1,100 SF
For Lease

$12.00/SF/YR
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77 Maryland Plaza

77 Maryland Plaza, Central West End Saint Louis, St. Louis, MO
Property

Office

6,221 SF
Availability

1 Space

6,221 SF
For Lease

$19.00/SF/YR
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4200 Sarpy Ave

4200 Sarpy Ave, Central West End Saint Louis, Saint Louis, MO
Property

Office

1,352 SF
Availability

1 Space

1,352 SF
Year Built

1988
For Lease

$1,402.70/MO
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42,120 SF Available for Lease - Prime Cortex Location

4300 Duncan Avenue, Central West End Saint Louis, St. Louis, MO
Property

Office
Availability

1 Space

42,120 SF
Year Built

2008
For Lease Contact for pricing
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6680 Chippewa Street

6680 Chippewa Street, St. Louis Hills, St. Louis, MO
Property

Office

6,753 SF
Availability

1 Space

2,392 SF
For Lease

$22.95/SF/YR
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3224 Locust Street
Kranzberg Arts Foundation
3224 Locust Street #401, St. Louis, MO
Amenities

Kitchen

Lounge area

Parking

Storage area
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217 N. 10th St.

217 N. 10th St., Downtown Saint Louis, St. Louis, MO
Property

Office

8,000 SF
Availability

1 Space

8,000 SF
For Lease

$14.00/SF/YR
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6170 Delmar Boulevard

6170 Delmar Boulevard, Skinker DeBaliviere, St. Louis, MO
Property

Office

1,140 SF
Availability

1 Space

1,140 SF
For Lease Contact for pricing
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4731 Delmar Boulevard
Elevation.Space
4731 Delmar Boulevard, St. Louis, MO
Services

Event Space

Meeting Room

Private Office
Amenities

A/V equipment

High-speed internet

High-speed wifi

Natural light

Office furniture

Projector

Videoconferencing

White boards

Window view
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22 N. Euclid Avenue

22 N. Euclid Avenue, Central West End Saint Louis, St. Louis, MO
Property

Office

750 SF
Availability

1 Space

750 SF
For Lease

$20.00/SF/YR
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1710-1714 Olive St.

1710-1714 Olive St., Downtown West Saint Louis, St. Louis, MO
Property

Retail

4,330 SF
Availability

1 Space

2,165 SF
For Lease

$18.00/SF/YR
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462 North Taylor St.

462 North Taylor St., Central West End Saint Louis, St. Louis, MO
Property

Office

561 SF
Availability

1 Space

561 SF
For Lease

$14.75/SF/YR
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16 Hampton Village Plaza

16 Hampton Village Plaza, South Hampton, St. Louis, MO
Property

Office

1,244 SF
Availability

1 Space

1,244 SF
For Lease

$12.00/SF/YR
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1916-1918 Carr Street

1916 Carr St, Carr Square, St. Louis, MO
Property

Office

2,000 SF
Availability

2 Spaces

2,000 SF
For Lease

$1,500.00/MO
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3460-70 Hampton Avenue

3460-70 Hampton Avenue, North Hampton, St. Louis, MO
Property

Office

20,320 SF
Availability

6 Spaces

8,500 SF
For Lease

$13.63/SF/YR
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1401 Dr Martin Luther King Dr

1401 Dr Martin Luther King Dr, Downtown West Saint Louis, Saint Louis, MO
Property

Office

6,200 SF
Availability

1 Space

6,200 SF
Year Built

2001
For Lease

$12.00/SF/YR
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St. Louis Marketplace

6660 Manchester Road, Clifton Heights, St. Louis, MO
Property

Retail

282,535 SF
Availability

5 Spaces

148,795 SF
Year Built

1992
For Lease

$7.00 - $13.00/SF/YR
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1905 S. Grand Blvd.

1905 S. Grand Blvd. St. Louis, Shaw, St. Louis, MO
Property

Office

5,055 SF
Availability

1 Space

5,055 SF
For Lease

$16.50/SF/YR
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4304 Manchester Ave.

4304 Manchester Ave., Forest Park South East, St. Louis, MO
Property

Office

4,200 SF
Availability

1 Space

4,200 SF
For Lease

$17.95/SF/YR
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601 East Red Bud Avenue
Cubework
601 East Red Bud Avenue, St. Louis, MO
Services

Event Space

Meeting Room

Private Office

Dedicated Desk
Amenities

Cleaning services

Complimentary coffee & tea

Game room

Gym

High-speed wifi

Kitchen

Loading docks

Lockers

Mail services

Office furniture
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Office Space For Lease in Campbell Plaza

1 Campbell Plaza, Southwest Garden, St. Louis, MO
Property

Office
Availability

1 Space

4,806 SF
Year Built

1972
For Lease Contact for pricing
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815 Olive St

815 Olive St, Downtown Saint Louis, Saint Louis, MO
Property

Office

7,319 SF
Availability

1 Space

7,319 SF
For Lease Contact for pricing
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2200 South Vandeventer Ave

2200 S Vandeventer Ave, Southwest Garden, St. Louis, MO
Property

Retail

5,430 SF
Availability

1 Space

3,800 SF
For Lease Contact for pricing
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6193-6195 Delmar Boulevard & 616 North Skinker Boulevard

6193-6195 Delmar Boulevard & 616 North Skinker Boulevard, West End Saint Louis, St. Louis, MO
Property

Retail

3,048 SF
Availability

4 Spaces

3,048 SF
For Lease Contact for pricing
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760 South 2nd Street

760 South 2nd Street, Downtown Saint Louis, St. Louis, MO
Property

Industrial

511,341 SF
Availability

1 Space

500,000 SF
Year Built

1906
For Lease Contact for pricing
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The Gill Building

622 Olive St, Downtown Saint Louis, St. Louis, MO
Property

Office

2,500 SF
Availability

2 Spaces

2,500 SF
For Lease

$2,250.00/MO
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350 North Skinker Boulevard

350 North Skinker Boulevard, Skinker DeBaliviere, St. Louis, MO
Property

Retail

1,761 SF
Availability

1 Space

1,761 SF
For Lease Contact for pricing
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255-257 Union Blvd

255-257 Union Blvd, DeBaliviere Place, Saint Louis, MO
Property

Retail

165,661 SF
Availability

1 Space

6,022 SF
Year Built

1918
For Lease

$18.00/SF/YR
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The Workshop
The Workshop
3965 Park Ave floor 2, St. Louis, MO

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Cortex K

4200 Clayton Avenue, Central West End Saint Louis, St. Louis, MO
Property

Office

140,000 SF
Availability

4 Spaces

120,000 SF
For Lease Contact for pricing
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4662 Washington Avenue

4662 Washington Avenue, Central West End Saint Louis, St. Louis, MO
Property

Retail

1,350 SF
Availability

1 Space

1,350 SF
Year Built

1950
For Lease

$17.00/SF/YR
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Frequently Asked Questions

Asking prices vary based on the property location, rating, amenities such as proximity to restaurants, cafes, and entertainment venues, as well as convenience of access to public transport, airports, and thoroughfares.

The average rent for office space in Saint Louis is $24.6 per square foot. The minimum rental rate for office space in Saint Louis is $13.63 per square foot.

For more details on Saint Louis office space rent and sales prices, as well as overall market quality and new construction data, see Saint Louis Office Market Trends.

Most experts recommend an average of between 75 and 150 square feet of office space per person. However, it is important to keep in mind that how much office space you ultimately need depends on your activity and how you need to use the space, as much as it does on how many people it should accommodate. If you already know what size office would best suit your needs, use the available space size filter at the top of the search page to focus your search on the best fit for you.

You’ll find a home for almost any size of business in Saint Louis, as the local office market offers a wide range of options. Office spaces currently on the market go up to as much as 71,965 square feet in size for an individual listing.
However, there is a variety of differently sized opportunities below that maximum. For your consideration, the median size of an office space for lease in Saint Louis is 4,000 square feet, and the average office space size here is 8,604 square feet.

You can find 246 office listing(s) for lease in Saint Louis, which add up to a total of 2,159,906 square feet. Availability on the market includes a variety of office use types, such as General Office, Creative Office, Medical Office, Shared Space, Street Retail.

The most common office use type currently available for lease in Saint Louis is General Office, which is offered in 142 or 57.72% of listings. The second-most frequent office use type listed here is Creative Office, which account for 14 or 5.69% of office space currently available. On the other end of the spectrum, the office use type least common among local listings is Office / Retail, which is available in 1 listing(s).

You can search 8 office sublease listing(s) in Saint Louis, which amount to a total of 82,658 square feet. Sublease opportunities on the market include General Office, Creative Office, Medical Office. The Saint Louis neighborhood or submarket with the most sublease listings available is Downtown Saint Louis.

The best choice of neighborhood for your office space will greatly depend on the elements that are most relevant to your business and your employees. However, a good criterion to start with is to look at the areas of the city that have the highest concentration of office properties, as these areas are generally well connected to transit options and have a good degree of amenity availability.

In Saint Louis, the greatest concentration of office space for lease opportunities is in Downtown Saint Louis, Downtown West Saint Louis, Forest Park South East.

Each individual’s commuting experience will of course be different depending on a number of factors. Check the location description details for the office listings that catch your eye, to get an overview of walkability, access to public transport, the quality of infrastructure dedicated to biking commuters, as well as the proximity to parking facilities, fuel stations, and other essential amenities.

The Saint Louis office market incorporates a mix of properties of various ages, ratings, construction grades, and other quality indicators. Roughly 44.72% of total office space listings in the city are in properties rated Class A. You will find the highest concentration of Class A office space in the Downtown Saint Louis neighborhood of Saint Louis. Class B office space accounts for 28.05% of spaces listed on the leasing market. The neighborhood with the most Class B office space is Downtown Saint Louis. Class C office space makes up 5.28% of office space available in Saint Louis.

Buildings completed in and since the year 2000 account for 6.33% of office properties in the city and incorporate a total of 189,698 square feet. About 12.66% of office space in Saint Louis is in buildings that have been renovated at least once since 2000.

Out of the office space listings currently available in Saint Louis, you can find 4 LEED-certified or LEED-proposed option(s). A total of 1 building(s) here earned a LEED-certification — certification level Silver (1).

There are, of course, a lot of things to factor in when you are looking for office space. Aspects including the accessibility of the location, the quality of the facility, the size of the space, the convenience of nearby amenities, the type and duration of the lease, and of course the cost are all part of the search and decision process. For a quick checklist of what you should take into account when researching the market, consider these seven tips for choosing the best office location for your business. Alternatively, for a comprehensive take on everything to consider when looking for office space, see our in-depth guide to finding office space for small or growing companies. The guide also includes insights from seasoned professionals and can serve as a helpful resource for growing companies, no matter their current size.

Are you looking to lease office space in the vicinity of your current location or in a particular neighborhood of Saint Louis? Using the interactive map, you can easily navigate to your preferred location and customize your search area around a specific point of interest. Select “Radius” from the Search Mode options menu, click on the map to set your search reference point, and expand the radius to select your desired search area. Browse available listings to find the best office space that meets your location, as well as other business needs.

Saint Louis, MO Office Inventory Breakdown

There are a number of factors that make a city attractive for businesses to relocate or expand, as well as for investors to enhance their portfolios through local acquisitions. Among the most important factors to consider are the size and quality of the local office market, which is an essential component of the local economy.

Total Office Space in Saint Louis: 23,868,759 Sq. Ft.

In 2024 the Saint Louis office market encompassed 23,868,759 square feet of space. Out of that total, 4,143,526 square feet were in office properties sized between 500,000 and 1,000,000 square feet. Meanwhile, 2,896,758 square feet were in office buildings sized between 50,000 and 100,000 square feet.
Class A office space makes up a 54.6% share of Saint Louis office inventory, while Class B office assets represent roughly 37.75% of the market total.

Saint Louis Office Market Breakdown by Building Size
Building Size Range	Total Square Feet	Share of Total Office
50k to 100k Sq. Ft.	2,896,758 Sq. Ft.	12.14%
100k to 500k Sq. Ft.	10,372,068 Sq. Ft.	43.45%
500k to 1M Sq. Ft.	4,143,526 Sq. Ft.	17.36%
> 1M Sq. Ft.	4,587,327 Sq. Ft.	19.22%

Saint Louis Office Market Breakdown by Building Quality Rating
Class	Total Square Feet	Share of Total Office
Class A	13,031,707 Sq. Ft.	54.6%
Class B	9,010,762 Sq. Ft.	37.75%
Class C	1,826,290 Sq. Ft.	7.65%

Data was provided by CommercialEdge, refers to properties larger than 50,000 square feet.

St. Louis, MO Office Market Overview

The St. Louis office market is robust and evolving. The city is rooted in industry and manufacturing, but healthcare and services have also grown rapidly here in the last decade. Anheuser-Busch has been a staple of the city since 1852 and it remains the North American headquarters for the beverage behemoth ABInBev. St. Louis also has several universities that have given rise to a budding biotech industry, with Washington University’s McDonnell Genome Institute being an integral part of the Human Genome Project.

Saint Louis, MO Office Spaces for Rent

Frequently Asked Questions

How much does office space cost in Saint Louis, MO?

How much office space do I need?

What types of office space can I lease in Saint Louis, MO?

Can I find sublease office space in Saint Louis, MO?

Where is the best location for office space in Saint Louis, MO?

How long is the average commute to work in Saint Louis, MO?

Where can I find the highest quality office space in Saint Louis, MO?

How do I find the best office space in Saint Louis, MO?

How can I find office space for rent near me?

Saint Louis, MO Office Inventory Breakdown

Total Office Space in Saint Louis: 23,868,759 Sq. Ft.

St. Louis, MO Office Market Overview

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