Bluffton, SC Office Spaces for Rent

Find the best Bluffton, SC office space among 9 for rent listings currently on the market.

Office/ Medical Building Fronting Hwy 278

5 Buck Island Rd, Bluffton, SC
Property

Office

17,525 SF
Availability

1 Space

17,525 SF
For Lease

$25.00/SF/YR
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SC, Bluffton - Hampton Lake Dr
Regus
7 Hampton Lake Drive, Bluffton, SC
Services

Virtual Office

Open Workspace

Private Office

Dedicated Desk
Amenities

24/7 security

Access to global network

Business address

Business lounge

Cleaning services

Ergonomic furniture

Lounge area

Mail services

Money-back guarantee

Office furniture
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Class A Office Space

27 Towne Drive, Bluffton, SC
Property

Office

17,341 SF
Availability

2 Spaces

5,058 SF
Year Built

2006
For Lease

$23.00/SF/YR
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Medical Office Space

29 Plantation Park Drive, Suite 203, Bluffton, SC
Property

Office

1,587 SF
Availability

1 Space

1,587 SF
For Lease

$28.00/SF/YR
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Plantation Commons II Office Suite for Lease

29 Plantation Park Drive, Unit 104-A, Bluffton, SC
Property

Office

646 SF
Availability

1 Space

646 SF
For Lease

$1,600.00/MO
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14 Westbury

14 Westbury Park Way, Suite 102, Bluffton, SC
Property

Office

1,449 SF
Availability

1 Space

1,449 SF
Year Built

2000
For Lease

$23.00/SF/YR
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Class "A" Office Building

1 Carecore Drive, Bluffton, SC
Property

Office

30,065 SF
Availability

2 Spaces

11,160 SF
For Lease

$25.00/SF/YR
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Retail / Office Space for Lease in Landmark Center

49 Pennington Drive, Unit 2G, Bluffton, SC
Property

Office

1,250 SF
Availability

1 Space

1,250 SF
For Lease

$2,000.00/MO
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Frequently Asked Questions

Asking prices vary based on the property location, rating, amenities such as proximity to restaurants, cafes, and entertainment venues, as well as convenience of access to public transport, airports, and thoroughfares.

The minimum rental rate for office space in Bluffton is $23 per square foot. Among listings of office space currently available for lease in Bluffton, the maximum rental rate is $28 per square foot.
Most experts recommend an average of between 75 and 150 square feet of office space per person. However, it is important to keep in mind that how much office space you ultimately need depends on your activity and how you need to use the space, as much as it does on how many people it should accommodate. If you already know what size office would best suit your needs, use the available space size filter at the top of the search page to focus your search on the best fit for you.

You’ll find a home for almost any size of business in Bluffton, as the local office market offers a wide range of options. Office spaces currently on the market go up to as much as 17,525 square feet in size for an individual listing.
You can find 9 office listing(s) for lease in Bluffton, which add up to a total of 33,617 square feet. Availability on the market includes a variety of office use types, such as General Office, Medical Office.

The most common office use type currently available for lease in Bluffton is General Office, which is offered in 3 or 42.86% of listings. The second-most frequent office use type listed here is Medical Office, which account for 1 or 14.29% of office space currently available.
Sublease opportunities on the market include General Office, Medical Office.
The best choice of neighborhood for your office space will greatly depend on the elements that are most relevant to your business and your employees. However, a good criterion to start with is to look at the areas of the city that have the highest concentration of office properties, as these areas are generally well connected to transit options and have a good degree of amenity availability.
Each individual’s commuting experience will of course be different depending on a number of factors. Check the location description details for the office listings that catch your eye, to get an overview of walkability, access to public transport, the quality of infrastructure dedicated to biking commuters, as well as the proximity to parking facilities, fuel stations, and other essential amenities.
The Bluffton office market incorporates a mix of properties of various ages, ratings, construction grades, and other quality indicators. Roughly 55.56% of total office space listings in the city are in properties rated Class A. Class B office space accounts for 22.22% of spaces listed on the leasing market.

Buildings completed in and since the year 2000 account for 42.86% of office properties in the city and incorporate a total of 21,628 square feet.
There are, of course, a lot of things to factor in when you are looking for office space. Aspects including the accessibility of the location, the quality of the facility, the size of the space, the convenience of nearby amenities, the type and duration of the lease, and of course the cost are all part of the search and decision process. For a quick checklist of what you should take into account when researching the market, consider these seven tips for choosing the best office location for your business. Alternatively, for a comprehensive take on everything to consider when looking for office space, see our in-depth guide to finding office space for small or growing companies. The guide also includes insights from seasoned professionals and can serve as a helpful resource for growing companies, no matter their current size.
Are you looking to lease office space in the vicinity of your current location or in a particular neighborhood of Bluffton? Using the interactive map, you can easily navigate to your preferred location and customize your search area around a specific point of interest. Select “Radius” from the Search Mode options menu, click on the map to set your search reference point, and expand the radius to select your desired search area. Browse available listings to find the best office space that meets your location, as well as other business needs.

Bluffton, SC Office Inventory Breakdown

There are a number of factors that make a city attractive for businesses to relocate or expand, as well as for investors to enhance their portfolios through local acquisitions. Among the most important factors to consider are the size and quality of the local office market, which is an essential component of the local economy.

Total Office Space in Bluffton: 314,129 Sq. Ft.

In 2025 the Bluffton office market encompassed 314,129 square feet of space.
Class A office space makes up a 19.45% share of Bluffton office inventory, while Class B office assets represent roughly 80.55% of the market total.

Bluffton Office Market Breakdown by Building Size
Building Size Range	Total Square Feet	Share of Total Office
50k to 100k Sq. Ft.	224,806 Sq. Ft.	71.56%

Bluffton Office Market Breakdown by Building Quality Rating
Class	Total Square Feet	Share of Total Office
Class A	61,102 Sq. Ft.	19.45%
Class B	253,027 Sq. Ft.	80.55%

Data was provided by CommercialEdge, refers to properties larger than 50,000 square feet.

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Bluffton, SC Office Spaces for Rent

Office/ Medical Building Fronting Hwy 278

SC, Bluffton - Hampton Lake Dr

Class A Office Space

Medical Office Space

Plantation Commons II Office Suite for Lease

14 Westbury

Class "A" Office Building

Retail / Office Space for Lease in Landmark Center

Frequently Asked Questions

Bluffton, SC Office Inventory Breakdown

Total Office Space in Bluffton: 314,129 Sq. Ft.

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