Pickens County, SC Office Spaces for Rent

Find the best Pickens County, SC office space among 5 for rent listings currently on the market.

444 Hampton Ave

444 Hampton Ave, Pickens, SC
Property

Office

4,265 SF
Availability

1 Space

1,175 SF
Year Built

1984
For Lease

$12.00/SF/YR
View Details (opens in new window)
Great Restaurant/Retail Space in Downtown Liberty!

25 South Commerce Street, Liberty, SC
Property

Office

1,972 SF
Availability

1 Space

1,972 SF
Year Built

1930
For Lease Contact for pricing
View Details (opens in new window)
Two-Story Medical Office Building in Easley’s Prime Medical Hub

201 Richard St, Easley, SC
Property

Office
Availability

1 Space

4,038 SF
Year Built

1971
For Lease Contact for pricing
View Details (opens in new window)
5208 Calhoun Memorial Hwy

5208 Calhoun Memorial Hwy, Easley, SC
Property

Office

1,220 SF
Availability

1 Space

1,220 SF
Year Built

1993
For Lease

$24.00/SF/YR
View Details (opens in new window)
107 S Pendleton St

107 S Pendleton St, Easley, SC
Property

Office

8,068 SF
Availability

1 Space

156 SF
For Lease

$499.00/MO
View Details (opens in new window)

Pickens County, SC Office Inventory Breakdown

There are a number of factors that make a city attractive for businesses to relocate or expand, as well as for investors to enhance their portfolios through local acquisitions. Among the most important factors to consider are the size and quality of the local office market, which is an essential component of the local economy.

Total Office Space in South Carolina: 185,157 Sq. Ft.

In 2025 the South Carolina office market encompassed 185,157 square feet of space.
Class A office space makes up a 26.99% share of South Carolina office inventory, while Class B office assets represent roughly 16.15% of the market total.

South Carolina Office Market Breakdown by Building Size
Building Size Range	Total Square Feet	Share of Total Office
100k to 500k Sq. Ft.	105,290 Sq. Ft.	56.87%

South Carolina Office Market Breakdown by Building Quality Rating
Class	Total Square Feet	Share of Total Office
Class A	49,968 Sq. Ft.	26.99%
Class B	29,899 Sq. Ft.	16.15%
Class C	105,290 Sq. Ft.	56.87%

Data was provided by CommercialEdge, refers to properties larger than 50,000 square feet.

About us

CommercialCafe is your go-to commercial real estate listing source. We partner with highly respected major brokerages from across the country to ensure high-quality listings that are updated frequently. Our online marketplace lists all commercial property types from office, coworking, retail, and industrial to special purpose properties.

CommercialCafe is a trusted Yardi brand and is an integral part of the CommercialEdge network — the fastest-growing network of online real estate marketplaces, which ranks on the 1st page of Google for all top markets, attracts more than 2 million monthly visits, and generates more than 350,000 broker contacts.

Pickens County, SC Office Spaces for Rent

444 Hampton Ave

Great Restaurant/Retail Space in Downtown Liberty!

Two-Story Medical Office Building in Easley’s Prime Medical Hub

5208 Calhoun Memorial Hwy

107 S Pendleton St

Pickens County, SC Office Inventory Breakdown

Total Office Space in South Carolina: 185,157 Sq. Ft.

Other Popular Searches

Popular Coworking Searches

About us

About Us

Our Tools